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Apr 27, 2014 (publication date) through Nov 13, 2025
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World Journal of Hepatology
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1948-5182
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright ©2014 Baishideng Publishing Group Co.
World J Hepatol. Apr 27, 2014; 6(4): 207-216
Published online Apr 27, 2014. doi: 10.4254/wjh.v6.i4.207
Table 1 Useful biomarkers for identifying epithelial-mesenchymal transition
BiomarkersMyofibroblastHepatic stellate cellHepatocyteCholangiocyte
α-SMA1++--
Vimentin1++--
Desmin1++--
ICAM-1++--
Collagen type IV++--
Fibronectin++--
Fibulin-2+---
IL-6 mRNA+---
NCAM+---
Synaptophysin+---
Neurotrophin+---
Neural growth factor+---
αB-crystalline+---
Tyrosine kinase+---
FSP-11+--
HSP471+--
CD95L-+--
α2-macroglobulin-+--
P100-+--
Reelin-+--
Fascin-+--
E-cadherin--++
Cytokeratin--++
K19---+
Albumin--+-
Slug1+?--
Twist1+?--
Snail1+?--
1Previously proven markers associated with epithelial-mesenchymal transition. α-SMA: α-smooth muscle actin; ICAM-1: Intercellular adhesion molecule-1; IL-6: Interleukin-6; NCAM: Neural cell adhesion molecule; FSP-1: Fibroblast-specific protein-1.
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