Nonalcoholic steatohepatitis in nonalcoholic fatty liver disease patients of Bangladesh

Table 1 Clinical, anthropometric and biochemical characteristics of the non-nonalcoholic steatohepatitis fatty liver and nonalcoholic steatohepatitis patients

Variable	NNFL	NASH	P
	n = 102	n = 75	value
Age, yr, (mean ± SD)	39.3 ± 9.4	41.0 ± 9.7	0.24
Sex: male/female	42/60	31/44	1.00
Body mass index (kg/m2)	27.8 ± 3.9	27.8 ± 4.6	0.998
Waist (cm)
Male	93.0 ± 5.5	93.0 ± 9.8	0.081
Female	95.8 ± 9.9	95.6 ± 11.0	0.927
HDL (mg/dL)
Male	36.3 ± 8.9	34.2 ± 6.5	0.337
Female	39.8 ± 10.3	39.2 ± 10.3	0.801
Serum triglyceride (mg/dL)	225.2 ± 165.8	239.8 ± 111.6	0.509
Insulin resistance index	1.8 ± 1.3	1.5 ± 0.7	0.337
Diabetes (present/absent)	13/86	25/48	0.001
Hypertension (present/absent)	17/65	17/48	0.555
Metabolic syndrome (present/absent)	41/41	39/32	0.328
ALT (U/L)	56.9 ± 38.8	56.3 ± 31.8	0.603
AST (U/L)	46.9 ± 63.7	46.1 ± 22.2	0.916
GGT (U/L)	40.4 ± 22.6	51.7 ± 32.8	0.05

NNFL: Non-nonalcoholic steatohepatitis fatty liver; NASH: Nonalcoholic steatohepatitis; HDL: High-density lipoproteins; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase.

Table 2 Multivariate regression analysis for the factors influencing the development of nonalcoholic steatohepatitis

Model	Unstandardized coefficients		Standardized coefficients	t	Sig.
	B	SE	Beta
Constant	1.247	0.517		2.411	0.018
BMI	0.014	0.018	0.124	0.780	0.438
Diabetes	0.260	0.125	0.227	2.084	0.040
Serum triglyceride	0.000	0.000	-0.105	-0.919	0.361
GGT	0.005	0.002	0.289	2.473	0.015
Waist circumference	-0.004	0.008	-0.077	-0.491	0.624

BMI: Body mass index; GGT: Gamma-glutamyl transpeptidase; Sig.: Significance.