Day-of-surgery rejection of donors in living donor liver transplantation

Table 1 The demographic data for donors of the two groups

	Group A donors (n = 65)			Group B donors (n = 22)			P value
	Range	Mean	SD	Range	Mean	SD
Age, yr	18-42	23.3	6.3	18-40	27.1	5.5	0.6
Weight, kg	46-86	64.7	10.1	51-93	66.8	11	0.38
Height, cm	140-190	166.5	8.4	152-186	169.3	10	0.44
BMI, kg/m2	14-28.9	23.5	3.4	17.4-28.4	23.3	3.4	0.88

BMI: Body mass index.

Table 2 The hospital stay and analgesia requirements for donors in each group

	Group A donors			Group B donors
	n = 65			n = 22			P value
	Range	Mean	SD	Range	Mean	SD
Hospital stay, d	4-7	4.9	1.1	4-6	4.8	0.6	0.75
No. of narcotic analgesia doses per admission, doses	3-10	6.3	2.1	2-8	5	1.5	0.42
No. of non-narcotic analgesia doses per admission, doses	10-17	12.9	1.8	12-16	13.1	1.2	0.31

Table 3 Donor complications in the two groups n (%)

	Group A donorsn = 65	Group B donorsn = 22	P value
Minor biliary leak	3 (4.6)	1 (4.5)	0.78
Wound seroma/hematoma	4 (6.2)	1 (4.5)	0.98
Wound infection	1 (1.5)	0	0.56
Incisional hernia	1 (1.5)	0	0.56
Ascites	1 (1.5)	0	0.56

Table 4 The indications for liver transplantation in each group of recipients n (%)

	Group A recipientsn = 65	Group B recipientsn = 22	P value
HCV cirrhosis	29 (44.6)	10 (45.4)	0.95
HBV cirrhosis	11 (16.9)	3 (13.6)	0.98
HBV and HCV cirrhosis	1 (1.5)	2 (9)	0.32
HCC	14 (21.5)	8 (36.3)	0.27
Cryptogenic cirrhosis	8 (12.3)	2 (9)	0.98
Wilson’s disease	3 (4.6)	0	0.73
Hyperoxaluria	4 (6.2)	0	0.55
Biliary atresia	0	2 (9)	0.1

HCV: Hepatitis C virus; HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus.

Table 5 Incidence of complications and retransplantation in each group of recipients n (%)

	Group A recipientsn = 65	Group B recipientsn = 22	P value
Biliary complications	20 (30.7)	9 (40.9)	0.50
Hepatic artery thrombosis	3 (4.6)	1 (4.5)	0.98
Portal vein thrombosis	4 (6.2)	1 (4.5)	0.78
Incisional hernia	3 (4.6)	2 (9)	0.80
Small-for-size syndrome	3 (4.6)	1 (4.5)	0.98
Primary non-function	1 (1.5)	0	0.56
Retransplantation	7 (10.8)	0	0.29

Table 6 Causes of graft-related deaths in both groups

	Group A recipientsn = 65	Group B recipientsn = 22	P value
Total number of graft-related deaths	13	3	0.73
Cholestatic HCV recurrence	1	0	0.56
HCC recurrence	2	0	0.99
Sepsis	3	1	0.99
Hepatic artery thrombosis	2	0	0.99
Portal vein thrombosis	3	2	0.80
Small-for-size syndrome	1	0	0.56

HCV: Hepatitis C virus; HCC: Hepatocellular carcinoma.

Table 7 The incidence of abnormal liver biopsy findings in groups A and B n (%)

	Group A donorsn = 65	Group B donorsn = 22	P value
Steatosis < 5%	18 (27.7)	5 (22.7)	0.86
Steatosis 5%-10%	4 (6.2)	2 (9)	0.64
Steatosis 10%-15%	6 (9.2)	0	0.32
Steatosis 15%-20%	1 (3.1)	0	0.56
Fibrosis (stage 0-1)	1 (1.5)	0	0.56