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©2010 Baishideng.
World J Hepatol. Jul 27, 2010; 2(7): 275-288
Published online Jul 27, 2010. doi: 10.4254/wjh.v2.i7.275
Published online Jul 27, 2010. doi: 10.4254/wjh.v2.i7.275
Table 1 Studies providing an estimate of nonalcoholic fatty liver disease in the pediatric population
| Authors/year/country | Sample size (n) | Age range (yr) | Clinical characteristics | Criteria | Prevalence (%) |
| Tominaga et al/1995/Japan[4] | 810 | 4-12 | Population-based (Japan) | Ultrasound echogenicity | 2.60 |
| Strauss et al/2000/USA[5] | 2450 | 12-18 | Population-based (NHANES III) | Elevated ALT (> 30 U/L) | 3.00 |
| Park et al/2005/Korea[6] | 1594 | 10-19 | Population-based (Korean NHANES) | Elevated ALT (> 40 U/L) | 3.20 |
| Schwimmer et al/2006/USA[7] | 742 | 2-19 | Population-based (Autopsy data, San Diego County) | Liver histology with ≥ 5% hepatocytes containing fat | 9.60 |
| Tominaga et al/2009/Japan[8] | 846 | 6-15 | Population-based (Japan) | Ultrasound echogenicity | 4.40 |
| Alavian et al/2009/Iran[9] | 966 | 7-18 | Population-based (Iran) | Ultrasound echogenicity | 7.10 |
| Tazawa et al/1997/Japan[10] | 310 | 6-11 | Obese cohort (% IBW/height over 120) | Elevated ALT (> 30 U/L) | 24.00 |
| Franzese et al/1997/Italy[11] | 72 | 4-15 | Obese cohort (% IBW/height over 120) | Ultrasound echogenicty | 53.00 |
| Guzzaloni et al/2000/Italy[12] | 375 | 8-16 | Obese cohort (BMI > 2 SD for chronologic age) | Ultrasound echogenicity | 42.00 |
| Chan et al/2004/China[13] | 84 | 7-18 | Obese cohort (BMI > 95th percentile) | Ultrasound echogenicty | 77.00 |
| Flores-Calderon et al/2005/Mexico[14] | 80 | 8-10 | Overweight (> 85th) and obese (> 95th percentile) cohort | Elevated ALT (> 40 U/L) | 42.00 |
| Louthan et al/2005/USA[15] | 181 | 4-17 | Obese cohort (BMI > 95th percentile) | Elevated ALT (> 40 U/L) | 8.00 |
| Quiros-Tejeira et al/2007/USA[16] | 517 | 4-19 | Obese cohort (BMI > 95th percentile) | Elevated ALT (> 97.5th percentile for age-and sex-specific reference values) | 24.00 |
| Rocha et al/2009/Brazil[17] | 175 | 12-15 | Obese cohort (WC > 75th percentile) | Ultrasound echogenicity | 1.70 |
| Denzer et al/2009/Germany[18] | 532 | 8-19 | Obese cohort (BMI > 90th percentile) | Ultrasound echogenicity | 28.00 |
| Papandreou et al/2009/Greece[19] | 43 | 9-13 | Obese cohort | Ultrasound echogenicity | 42.00 |
- Citation: Pacifico L, Poggiogalle E, Cantisani V, Menichini G, Ricci P, Ferraro F, Chiesa C. Pediatric nonalcoholic fatty liver disease: A clinical and laboratory challenge. World J Hepatol 2010; 2(7): 275-288
- URL: https://www.wjgnet.com/1948-5182/full/v2/i7/275.htm
- DOI: https://dx.doi.org/10.4254/wjh.v2.i7.275