Anti-oxidative stress treatment and current clinical trials

Table 1 Clinical trials on anti-oxidative stress-related treatment

NCT number	Condition(s)	Category	Intervention(s)	Phase(s)
NCT05511766	Cirrhosis, hepatic encephalopathy	Drug	Allopurinol 300 mg, Atorvastatin 20 mg	2 and 3
NCT01054768	Anemia, sickle cell	Drug	Alpha-lipoic acid and acetyl-L-carnitine	2
NCT05558878	Diabetic peripheral neuropathy	Drug	Ambroxol oral product	NA
NCT00916448	Endotoxemia, multi-organ dysfunction	Drug	Atazanavir, E. coli endotoxin	NA
NCT03820245	Oxidative stress, atherosclerosis	Dietary	Bixin, norbixin, lycopene	NA
NCT05957432	Helicobacter pylori infection	Drug	Black seed oil, vonoprazan, amoxicillin, clarithromycin	2
NCT03529396	Vivax malaria, glucose-6-phosphate dehydrogenase	Drug	Chloroquine, primaquine	2
NCT03935958	Disorder in renal transplantation	Dietary	Curcumin	NA
NCT04458116	Coronary artery disease	Dietary	Curcumin	NA
NCT03514667	Metabolic syndrome	Dietary	Nanomicielle curcumin	NA
NCT04413266	Kidney diseases, peritoneal dialysis	Dietary	Curcumin supplementation	NA
NCT05966441	Chemotherapy peripheral neuropathy	Dietary	Curcumin, paclitaxel	2
NCT06083480	Osteoarthritis, knee arthroplasty	Drug	GlyNAC (combined glycine and N-acetylcysteine)	4
NCT01854294	Amyotrophic lateral sclerosis	Drug	GM604	2
NCT01891500	Persistent fetal circulation syndrome	Drug	Inhaled nitric oxide, nitrogen Gas	4
NCT05033639	Necrotizing enterocolitis	Drug	Melatonin 6 mg	1 and 2
NCT02463318	Multiple sclerosis	Drug	Melatonin, hydrogen peroxide	NA
NCT03557229	Septic shock	Drug	Melatonin, vitamins C and E, N-acetyl cysteine	3
NCT02587741	Diabetic retinopathy	Drug	Metformin, lantus, Novomix30	1
NCT01501929	Hypertension	Drug	Metoprolol succinate, nebivolol	4
NCT05742698	Frontotemporal dementia	Drug	Nabilone	2
NCT02294591	Bipolar disorder	Drug	N-acetyl cysteine	2
NCT02972398	Major depressive disorders	Drug	N-acetyl cysteine	NA
NCT01612221	Risk for melanoma	Drug	N-acetyl cysteine	2
NCT05611086	Lymphoblastic leukemia	Drug	N-acetyl cysteine	4
NCT01501110	Ischemic heart disease	Drug	N-acetyl cysteine	4
NCT05460858	Female infertility, endometrioma	Drug	N-acetyl cysteine	3
NCT03956888	Chronic obstructive pulmonary disease	Drug	N-acetyl cysteine	3
NCT01907061	Acute renal failure	Drug	N-acetyl cysteine	NA
NCT02124525	Tobacco smoking, inflammation	Drug	N-acetyl cysteine	3
NCT04792021	SARS-CoV-2 infection	Drug	N-acetyl cysteine	3
NCT04154982	Cardiac arrhythmia	Drug	N-acetyl cysteine	2
NCT03596125	Preterm delivery	Drug	N-acetyl cysteine	2 and 3
NCT04732000	Surgical recovery	Drug	N-acetyl cysteine	2
NCT02252341	Bipolar disorder	Dietary	N-acetyl cysteine	4
NCT01587001	Pulmonary sarcoidosis	Dietary	N-acetyl cysteine	NA
NCT01962961	HIV infection, endothelial dysfunction	Dietary	N-acetyl cysteine	1 and 2
NCT04440280	Fuchs endothelial corneal dystrophy	Drug	N-acetyl cysteine solution, visine	2
NCT02117700	Obesity, NAFLD, cardiovascular disease	Dietary	N-acetyl cysteine 600 mg	1 and 2
NCT05589584	Steatosis, non-fatty liver	Drug	N-acetyl cysteine	3
NCT04459052	Parkinson disease	Dietary	N-acetyl cysteine, F18 Fluorodopa	2
NCT01384591	Aging	Drug	N-acetyl cysteine, losartan	1 and 2
NCT03056014	Type 1 diabetes	Drug	N-acetyl cysteine, omega-6 fish oil	1
NCT04022161	Cardiovascular, endothelial dysfunction	Drug	Nitrogen gas for inhalation, nitric oxide	2
NCT03273413	Autosomal dominant polycystic kidney	Drug	Pravastatin	4
NCT02161653	Severe alcoholic hepatitis	Drug	Prednisone, metadoxine, pentoxifylline	4
NCT05770297	Endometriosis, dysmenorrhea	Dietary	Propolis	NA
NCT05753436	Diabetes, dyslipidemias, hypertension	Dietary	Puritans pride turmeric curcumin	2
NCT01663103	Renal insufficiency, chronic	Drug	Rilonacept	4
NCT01388478	Alzheimer's disease	Drug	R-pramipexole	2
NCT03738176	Oral lichen planus	Drug	Sesame oil, triamcinolone	1
NCT03402204	Ischemic stroke	Drug	Simvastatin 10 mg, simvastatin 40 mg	3
NCT05145270	Major depressive disorder	Dietary	Sulforaphane, escitalopram	4
NCT05149716	Oxidative stress	Dietary	Taurine	NA

NAFLD: Non-alcoholic fatty liver disease; NA: Not applicable.