Khrais A, Kahlam A, Tahir A, Shaikh A, Ahlawat S. Outcomes of gout in patients with cirrhosis: A national inpatient sample-based study. World J Hepatol 2023; 15(2): 303-310 [PMID: 36926244 DOI: 10.4254/wjh.v15.i2.303]
Corresponding Author of This Article
Ayham Khrais, DO, Staff Physician, Division of Medicine, Rutgers New Jersey Medical School, 150 Bergen Street, Newark, NJ 07103, United States. ak2017@njms.rutgers.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
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World J Hepatol. Feb 27, 2023; 15(2): 303-310 Published online Feb 27, 2023. doi: 10.4254/wjh.v15.i2.303
Table 1 Patient sex at birth for gout with and without a history of cirrhosis
Patients without cirrhosis, n = 1491829
Patients with cirrhosis, n = 36948
OR
95%CI
P value
Percentage
n
Percentage
n
Sex at birth
Female
33.17
494890
25.37
9372
0.685
0.669-0.701
< 0.05
Male
66.83
996939
74.63
27576
Table 2 Differences in age distribution among patients hospitalized for gout with and without a history of cirrhosis
Patients without cirrhosis
Patients with cirrhosis
Mean difference
95%CI
P value
Mean
SD
SE mean
Mean
SD
SE mean
Age at admission (yr)
70.37
13.53
0.011
66.21
12.33
0.064
4.167 ± 0.071
4.027-4.306
< 0.05
Table 3 Racial characteristics in patients hospitalized for gout with and without a history of cirrhosis
Race
Patients without cirrhosis
Patients with cirrhosis
P value
%
n
%
n
Caucasian
71.0
890040
69.1
22725
< 0.05
Black
18.6
233005
17.4
5723
Hispanic
4.4
55174
7.4
2426
Asian or Pacific Islander
3.6
45217
3.6
1184
Native American
0.3
4289
0.4
122
Other
2.0
25351
2.1
703
Table 4 Primary outcomes in gout among hospitalized patients with and without cirrhosis
Patients without cirrhosis
Patients with cirrhosis
OR
95%CI
P value
AOR
ACI
Adjusted P value
Percentage
n
Percentage
n
Mortality
2.03
30286
5.49
2029
2.804
2.678-2.937
< 0.050
3.092
2.939-3.252
< 0.05
Gout flare
2.77
41282
2.89
1066
1.044
0.982-1.110
0. 171
0.816
0.765-0.871
< 0.05
Tophi
0.75
11202
0.97
358
1.293
1.164-1.438
< 0.050
1.025
0.914-1.149
0.677
Uric acid nephrolithiasis
0.02
374
0.02
9
0.972
0.502-1.882
0.932
1.037
0.530-2.030
0.915
Nephropathy
0.02
283
0.01
5
0.713
0.295-1.727
0.452
0.548
0.223-1.346
0.19
Arthrocentesis
2.45
36611
2.21
818
0.900
0.839-0.965
< 0.050
0.741
0.686-0.800
< 0.05
Joint injection
0.72
10673
0.52
192
0.725
0.628-0.837
< 0.050
0.713
0.610-0.833
< 0.050
Septic Arthritis
0.31
4637
0.31
114
0.993
0.824-1.196
0.939
0.997
0.821-1.211
0.977
Citation: Khrais A, Kahlam A, Tahir A, Shaikh A, Ahlawat S. Outcomes of gout in patients with cirrhosis: A national inpatient sample-based study. World J Hepatol 2023; 15(2): 303-310