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©The Author(s) 2022.
World J Hepatol. Mar 27, 2022; 14(3): 551-558
Published online Mar 27, 2022. doi: 10.4254/wjh.v14.i3.551
Published online Mar 27, 2022. doi: 10.4254/wjh.v14.i3.551
Table 1 Baseline characteristics of patients with hypothyroidism in explorys database
| Parameter | Hypothyroidism | ||
| Present (%) | Absent (%) | ||
| Age (yr) | 18-65 | 1335370 (48.3) | 21097850 (60.5) |
| > 65 | 1402550 (50.7) | 6951210 (19.9) | |
| Gender | Female | 2087040 (75.5) | 18562590 (53.2) |
| Race | Caucasian | 2267940 (82.0) | 20165960 (57.8) |
| African-American | 196720 (7.1) | 4120940 (11.8) | |
| Asian | 40710 (1.5) | 539190 (1.5) | |
| Comorbidities | HTN | 1665090 (60.2) | 7441760 (21.3) |
| T2DM | 790680 (28.6) | 3114700 (8.9) | |
| Dyslipidemia | 1716240 (62.1) | 6469880 (18.5) | |
| Obesity | 753060 (27.2) | 3391060 (9.7) | |
| Metabolic syndrome | 54440 (2.0) | 2709750 (7.8) | |
Table 2 Multivariate analysis for risk factors in individuals with non-alcoholic fatty liver disease
| Parameter | Odds ratio | 95%CI | P value |
| Age (18-65) | 1.658 | 1.524-1.804 | < 0.0001 |
| Male | 1.008 | 0.934-1.088 | 0.841 |
| Caucasian | 1.636 | 1.489-1.799 | < 0.0001 |
| Obesity | 3.616 | 3.318-3.940 | < 0.0001 |
| T2DM | 2.178 | 1.994-2.379 | < 0.0001 |
| Dyslipidemia | 2.346 | 2.121-2.596 | < 0.0001 |
| Hypertension | 1.326 | 1.201-1.465 | < 0.0001 |
| Metabolic syndrome | 4.782 | 4.782-5.460 | < 0.0001 |
| Hypothyroidism | 1.587 | 1.388-1.815 | < 0.0001 |
| Hypothyroidism on Thyroxine replacement therapy | 1.106 | 0.952-1.285 | 0.188 |
- Citation: Almomani A, Hitawala AA, Kumar P, Alqaisi S, Alshaikh D, Alkhayyat M, Asaad I. Prevalence of hypothyroidism and effect of thyroid hormone replacement therapy in patients with non-alcoholic fatty liver disease: A population-based study. World J Hepatol 2022; 14(3): 551-558
- URL: https://www.wjgnet.com/1948-5182/full/v14/i3/551.htm
- DOI: https://dx.doi.org/10.4254/wjh.v14.i3.551