Non-alcoholic steatohepatitis and the risk of myocardial infarction: A population-based national study

Table 1 Baseline characteristics of subjects with co-morbidities included in this study

	Total cohort	Proportion (%)	NASH cohort	Proportion (%)
Total cohort	55099280		43170
Male gender	24569555	45	17380	40
Age above 65 yr	15333620	28	17020	39
Essential hypertension	11043970	20	32040	74
Hyperlipidemia	9539460	17	31030	72
Smoking	4993910	9	9920	23
Diabetes mellitus	4785840	9	24640	57
Obesity	4226640	8	25570	59

NASH: Non-alcoholic steatohepatitis.

Table 2 Unadjusted odds ratio of having an associated diagnosis of myocardial infarction based on subjects’ co-morbidities

	Odds ratio	95%CIb
Hyperlipidemia	40.13	39.47-40.79
Essential hypertension	27.43	27.00-7.86
Male gender	17.61	17.41-17.81
Diabetes mellitus	12.57	12.44–12.71
NASH	10.66	9.58-10.94
Obesity	8.19	8.09-8.28
Smoking	6.71	6.64-6.79
Age above 65 yr	4.97	4.92-5.03

^bP < 0.01 unless otherwise stated. NASH: Non-alcoholic steatohepatitis; CI: Confidence interval.

Table 3 Adjusted odds ratio for acute myocardial infarction based on subject co-morbidities

	Odds ratio	95%CIb
Hyperlipidemia	8.39	8.21-8.58
Hypertension	3.11	3.05-3.17
Smoking	2.83	2.79-2.87
Diabetes mellitus	1.89	1.86-1.91
Obesity	1.78	1.75-1.80
Male	1.53	1.51-1.55
NASH	1.5	1.40-1.62
Age above 65 yr	1.47	1.45-1.49

^bP < 0.01 unless otherwise stated. NASH: Non-alcoholic steatohepatitis; CI: Confidence interval.