Impact of psychosocial comorbidities on clinical outcomes after liver transplantation: Stratification of a high-risk population

Table 1 Demographic data

	Value	%
Median age	59.30	12.44
Sex: Male (%): Female (%)	243 (62.15)	148 (37.85)
Etiology of liver disease
Alcohol	45	11.54
Nonalcoholic steatohepatitis	47	12.05
Hepatitis C	48	12.31
Hepatitis B	1	0.26
Hepatocellular carcinoma	1	0.26
Autoimmune hepatitis	20	5.13
Cryptogenic	1	0.26
Multi-visceral	14	3.59
Primary sclerosing cholangitis	25	6.41
Primary biliary cholangitis	12	3.08
Alpha-1-antitrypsin-Deficiency	5	1.28
Hepatic vein thrombosis	2	0.51
Hemochromatosis	1	0.26
Total parental nutrition related	1	0.26
Polycystic liver disease	1	0.26
Familial intrahepatic cholestasis	1	0.26
Cholangiocarcinoma	2	0.51
Primary oxaluria	3	0.77
Multiple	161	41.0

Table 2 Psychiatric history

Psychiatric diagnosis	Value	%
None	250	63.94
Major depression	78	19.95
Generalized anxiety	12	3.07
Bipolar disorder	5	1.28
Attention deficit disorder	1	0.26
Panic disorder	1	0.26
Conversion disorder	1	0.26
Multiple	43	10.98

Table 3 Psychiatric decompensation

		Psychosocial decompensation
		No	Yes	Total
	No	225 (90.0)	25 (10.0)	250
Psychiatric history	Yes	114 (80.85)	27 (19.15)	141
	Total	339	52	391
P = 0.013
	No	266 (88.96)	33 (11.04)	299
Psychiatric treatment	Yes	73 (79.35)	19 (20.65)	92
	Total	339	52	391
P = 0.022

Table 4 Recidivism

		Recidivism
		No	Yes	Total
	No	334 (98.82)	4 (1.18)	338
Substance use	Yes	49 (94.23)	3 (5.77)	52
	Total	383	7	390
P = 0.05
	No	371 (98.67)	5 (1.33)	376
Non-compliance		13 (86.67)	2 (13.33)	15
		384	7	391
P = 0.03

Table 5 Graft failure

		Graft failure
		No	Yes	Total
	No	253 (67.29)	123 (32.71)	376
Non-compliance	Yes	6 (40.0)	9 (60.0)	15
	Total	259	132	391
P = 0.047