Hepatitis C virus antigens enzyme immunoassay for one-step diagnosis of hepatitis C virus coinfection in human immunodeficiency virus infected individuals

Table 1 Blinded 147 serum samples in four groups for hepatitis C virus antigens enzyme immunoassay

Group	Diagnosis	Cases	HCV infection	HIV infection
1	No HCV/HIV	10	No (anti-HCV -/HCV PCR -)	No (anti-HIV -)
2	HCV alone	54	Yes (anti-HCV +/HCV PCR +)	No (anti-HIV -)
3	HCV/viremic HIV	38	Yes (anti-HCV +/HCV PCR +)	Yes (anti-HIV +/HIV PCR +)
4	HCV/non-viremic HIV	45	Yes (anti-HCV +/HCV PCR +)	Yes (anti-HIV +/HIV PCR -)
Total		147

HCV: Hepatitis C virus; HIV: Human immunodeficiency virus.

Table 2 The accordance of serum hepatitis C virus antigens enzyme immunoassay test results to hepatitis C virus RNA PCR in sera with hepatitis C virus monoinfection

Groups	Interpretation	Cases	Serum HCV-Ags EIA
			Positive (%)	Negative (%)
1 (anti-HCV -/HCV RNA -)	No HCV infection	10	0 (0.0%)	10 (100.0%)
2 (anti-HCV +/HCV RNA +)	Chronic HCV infection	54	54 (100.0%)	0 (0.0%)
Subtotal		64	54	10

HCV: Hepatitis C virus; HCV-Ags EIA: HCV-antigens enzyme immunoassay.

Table 3 Accordance of serum hepatitis C virus antigens enzyme immunoassay to hepatitis C virus PCR testing results in sera with hepatitis C virus/human immunodeficiency virus coinfection

Groups	HIV status	Cases	Serum HCV-Ags EIA
			Positive (%)	Negative (%)
1 (anti-HCV +/HCV RNA +)	Viremic HIV infection	38	38 (100.0%)	0 (0.0%)
2 (anti-HCV +/HCV RNA +)	No viremic HIV infection	45	45 (100.0%)	0 (0.0%)
Subtotal		83	83	0

HIV: Human immunodeficiency virus; HCV: Hepatitis C virus; HCV-Ags EIA: HCV-antigens enzyme immunoassay.