Difficulties in diagnosing acute kidney injury post liver transplantation using serum creatinine based diagnostic criteria

Figure 1 Cohort of 329 adult patients undergoing liver transplantation at the Royal Free Hospital. Serum creatinine measured using an enzymatic method shows a significant increase between the pre-operative and 1^st post-operative day and the 3^rd and 7^th post-operative days respectively. Only 2.4% developed acute kidney injury stage 3 on serum creatinine criteria alone, suggesting that the most probable cause for the significant increase was due to changes in serum creatinine measurement due to a reduction in bilirubin and other chromagens, and the use of immunophyllins as immunosuppressive agents.