Implications of gut microbiota in hepatic and pancreatic diseases: Gut-liver-pancreas axis

doi:10.4254/wjh.v17.i9.109965

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Sep 27, 2025 (publication date) through Sep 25, 2025

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Sep 27, 2025; 17(9): 109965
Published online Sep 27, 2025. doi: 10.4254/wjh.v17.i9.109965

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Figure 1 Schematic representation of bile acid relation with gut microbiota. Gut microbiota can metabolize bile acid (BA) into secondary BAs through various enzymatic reactions, including deconjugation and dehydroxylation, which has effects on adipose tissue, pancreas, and immune cells through FXR and TGR-5 signaling pathways. BA: Bile acid.

Citation: Abdelwahab MM, Ghattas AS, Tawheed A. Implications of gut microbiota in hepatic and pancreatic diseases: Gut-liver-pancreas axis. World J Hepatol 2025; 17(9): 109965
URL: https://www.wjgnet.com/1948-5182/full/v17/i9/109965.htm
DOI: https://dx.doi.org/10.4254/wjh.v17.i9.109965