Bone marrow progenitor cells do not contribute to liver fibrogenic cells

doi:10.4254/wjh.v4.i10.274

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Oct 27, 2012 (publication date) through Nov 26, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Oct 27, 2012; 4(10): 274-283
Published online Oct 27, 2012. doi: 10.4254/wjh.v4.i10.274

Bone marrow progenitor cells do not contribute to liver fibrogenic cells

Bruno Diaz Paredes, Lanuza Alaby Pinheiro Faccioli, Luiz Fernando Quintanilha, Karina Dutra Asensi, Camila Zaverucha do Valle, Paulo César Canary, Christina Maeda Takiya, Antonio Carlos Campos de Carvalho, Regina Coeli dos Santos Goldenberg

Bruno Diaz Paredes, Lanuza Alaby Pinheiro Faccioli, Luiz Fernando Quintanilha, Karina Dutra Asensi, Camila Zaverucha do Valle, Christina Maeda Takiya, Antonio Carlos Campos de Carvalho, Regina Coeli dos Santos Goldenberg, Carlos Chagas Filho Biophysics Institute, Rio de Janeiro 21941-902, Brazil

Paulo César Canary, Radiology Department, Clementino Fraga Filho University Hospital , Rio de Janeiro 22909-538, Brazil

Author contributions: Paredes BD and Faccioli LAP contributed equally to this work and participated in the experimental design, performed flow cytometry, fluorescence assays, and analyzed the data; Quintanilha LF performed mouse liver injury and data analysis; Asensi KD performed bone marrow transplantation and data analysis; Zaverucha-do-Valle C performed confocal microscopy and data analysis; Canary PC performed mouse whole-body irradiation and data analysis; Takiya CM performed histology and data analysis; Campos-de-Carvalho AC participated in the experimental design and statistical analysis; Goldenberg RCS designed and supervised the study, execution, analysis and approved the final version; and all authors participated in manuscript preparation.

Supported by Brazilian Council for Scientific and Technological Development; Coordination for the Improvement of Higher Education Personnel; Rio de Janeiro State Research Supporting Foundation and Ministry of Health

Correspondence to: Regina Coeli dos Santos Goldenberg, PhD, Carlos Chagas Filho Biophysics Institute, Carlos Chagas Filho Avenue, 373, Health Sciences Center, Corridor G, 2nd floor/room 53-University City, Rio de Janeiro 21941-902, Brazil. rcoeli@biof.ufrj.br

Telephone: +55-21-25626559 Fax: +55-21-25626559

Received: December 6, 2011
Revised: October 24, 2012
Accepted: October 26, 2012
Published online: October 27, 2012

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