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For: Zhai B, Sun XY. Mechanisms of resistance to sorafenib and the corresponding strategies in hepatocellular carcinoma. World J Hepatol 2013; 5(7): 345-352 [PMID: 23898367 DOI: 10.4254/wjh.v5.i7.345]
URL: https://www.wjgnet.com/1948-5182/full/v5/i7/345.htm
Number Citing Articles
1
Seunghyun Lee, Jung Hoon Kim, Jae Hwan Lee, Jeong Hwa Lee, Joon Koo Han. Non-invasive monitoring of the therapeutic response in sorafenib-treated hepatocellular carcinoma based on photoacoustic imagingEuropean Radiology 2018; 28(1) doi: 10.1007/s00330-017-4960-3
2
Dizhong Chen, Chang Kai Soh, Wei Huang Goh, Haishan Wang. Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular CarcinomaJournal of Medicinal Chemistry 2018; 61(4) doi: 10.1021/acs.jmedchem.7b01465
3
Wei Chen, Weikai Xiao, Kunsong Zhang, Xiaoyu Yin, Jiaming Lai, Lijian Liang, Dong Chen. Activation of c-Jun predicts a poor response to sorafenib in hepatocellular carcinoma: Preliminary Clinical EvidenceScientific Reports 2016; 6(1) doi: 10.1038/srep22976
4
Jimin Dai, Qichao Huang, Kunwei Niu, Bo Wang, Yijie Li, Chen Dai, Zhinan Chen, Kaishan Tao, Jingyao Dai. Sestrin 2 confers primary resistance to sorafenib by simultaneously activating AKT and AMPK in hepatocellular carcinomaCancer Medicine 2018; 7(11) doi: 10.1002/cam4.1826
5
Lei Fan, Xiang Huang, Jing Chen, Kai Zhang, Yan-hong Gu, Jing Sun, Shi-yun Cui. Long Noncoding RNA MALAT1 Contributes to Sorafenib Resistance by Targeting miR-140-5p/Aurora-A Signaling in Hepatocellular CarcinomaMolecular Cancer Therapeutics 2020; 19(5) doi: 10.1158/1535-7163.MCT-19-0203
6
Yuexiang Niu, Gongen Tang, Xiuli Wu, Chaoyu Wu. LncRNA NEAT1 modulates sorafenib resistance in hepatocellular carcinoma through regulating the miR-149-5p/AKT1 axisSaudi Journal of Gastroenterology 2020; 26(4) doi: 10.4103/sjg.SJG_4_20
7
Fangfang Duan, Hao Wu, Dongwei Jia, Weicheng Wu, Shifang Ren, Lan Wang, Shushu Song, Xinying Guo, Fenglin Liu, Yuanyuan Ruan, Jianxin Gu. O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesisJournal of Hepatology 2018; 68(6) doi: 10.1016/j.jhep.2018.02.003
8
Jiuwei Zhang, Yaodong Chen, Jing Lin, Ruimei Jia, Tingting An, Tianxiu Dong, Yu Zhang, Xiuhua Yang. Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma DNA and Cell Biology 2020; 39(3) doi: 10.1089/dna.2019.4990
9
Xueying Ren, Yanchun Li, Yi Zhou, Wanye Hu, Chen Yang, Qiangan Jing, Chaoting Zhou, Xu Wang, Jiayu Hu, Luyang Wang, Jing Yang, Hairui Wang, Haifeng Xu, Huanjuan Li, Xiangmin Tong, Ying Wang, Jing Du. Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosisRedox Biology 2021; 46 doi: 10.1016/j.redox.2021.102122
10
Aastha Jindal, Anusha Thadi, Kunwar Shailubhai. Hepatocellular Carcinoma: Etiology and Current and Future DrugsJournal of Clinical and Experimental Hepatology 2019; 9(2) doi: 10.1016/j.jceh.2019.01.004
11
MINORU TOMIZAWA, FUMINOBU SHINOZAKI, YASUFUMI MOTOYOSHI, TAKAO SUGIYAMA, SHIGENORI YAMAMOTO, MAKOTO SUEISHI. Picropodophyllin and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cellsOncology Letters 2014; 8(5) doi: 10.3892/ol.2014.2484
12
Danyu Du, Chan Liu, Mengyao Qin, Xiao Zhang, Tao Xi, Shengtao Yuan, Haiping Hao, Jing Xiong. Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinomaActa Pharmaceutica Sinica B 2022; 12(2) doi: 10.1016/j.apsb.2021.09.019
13
Bo Zhai, Fengli Hu, Haijiang Yan, Dali Zhao, Xin Jin, Taishi Fang, Shangha Pan, Xueying Sun, Lishan Xu, Yu-Jia Chang. Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum StressPLOS ONE 2015; 10(9) doi: 10.1371/journal.pone.0138485
14
Maurice Michel, Marcus Hollenbach, Sabine Pohl, Cristina Ripoll, Alexander Zipprich. Inhibition of Glyoxalase-I Leads to Reduced Proliferation, Migration and Colony Formation, and Enhanced Susceptibility to Sorafenib in Hepatocellular CarcinomaFrontiers in Oncology 2019; 9 doi: 10.3389/fonc.2019.00785
15
Yong‐Syuan Chen, Chien‐Hsing Lee, Yi‐Hsien Hsieh, Hui‐Ling Chiou, Ming‐Chun Hung, Hsiang‐Lin Lee. Sorafenib, a Tyrosine Kinase Inhibitor, Synergistically Enhances the Ferroptosis Effects of Asiatic Acid in Hepatocellular Carcinoma CellsEnvironmental Toxicology 2025; 40(1) doi: 10.1002/tox.24415
16
Yijie Su, Sirui Huang, Yang Duan, Liang Zhang, Shengyun Feng, Yingge Lv, Bei Lan, Chenghao Xuan. ATF7IP inhibits Sorafenib-induced ferroptosis in hepatocellular carcinoma cells by inhibiting CYB5R2 transcription and stabilizing PARK7 proteinRedox Biology 2025; 85 doi: 10.1016/j.redox.2025.103786
17
Kija Malale, Jili Fu, Liewang Qiu, Ke Zhan, Xiuni Gan, Zhechuan Mei. <p>Hypoxia-Induced Aquaporin-3 Changes Hepatocellular Carcinoma Cell Sensitivity to Sorafenib by Activating the PI3K/Akt Signaling Pathway</p>Cancer Management and Research 2020;  doi: 10.2147/CMAR.S243918
18
Alexandru Șandor, Ionel Fizeșan, Ioana Ionuț, Gabriel Marc, Cristina Moldovan, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, Andreea-Elena Petru, Ioana Macasoi, Ovidiu Oniga. Discovery of A Novel Series of Quinazoline–Thiazole Hybrids as Potential Antiproliferative and Anti-Angiogenic AgentsBiomolecules 2024; 14(2) doi: 10.3390/biom14020218
19
V. Schinzari, V. Barnaba, S. Piconese. Chronic hepatitis B virus and hepatitis C virus infections and cancer: synergy between viral and host factorsClinical Microbiology and Infection 2015; 21(11) doi: 10.1016/j.cmi.2015.06.026
20
Bao Chen Yang, Po Sing Leung. Irisin Is a Positive Regulator for Ferroptosis in Pancreatic CancerMolecular Therapy - Oncolytics 2020; 18 doi: 10.1016/j.omto.2020.08.002
21
Yomna Elleithi, Amal El-Gayar, Mohamed N. Amin. Autophagy modulation attenuates sorafenib resistance in HCC induced in ratsCell Death & Disease 2024; 15(8) doi: 10.1038/s41419-024-06955-5
22
Gang Hu, Yixin Zhang, Kedong Ouyang, Fubo Xie, Houshun Fang, Xueyang Yang, Kunyan Liu, Zongyu Wang, Xuzhen Tang, Jibin Liu, Lei Yang, Zhenzhou Jiang, Weikang Tao, He Zhou, Luyong Zhang. In�vivo acquired sorafenib‑resistant patient‑derived tumor model displays alternative angiogenic pathways, multi‑drug resistance and chromosome instabilityOncology Letters 2018;  doi: 10.3892/ol.2018.9078
23
Ting Liu, Xin Liu, Wenhua Li. Tetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapyOncotarget 2016; 7(26) doi: 10.18632/oncotarget.8315
24
Yiming Cheng, Xiaochen Wang, Shuyu Huang, Liang Zhang, Bei Lan, Xuanyuan Li, Hao Chen, Zhenfeng Liu, Yijie Su, Lishan Xi, Shengyun Feng, Yanxuan Guo, Jun Zhou, Yingmei Wang, Chenghao Xuan. A CRISPR-Cas9 library screening identifies CARM1 as a critical inhibitor of ferroptosis in hepatocellular carcinoma cellsMolecular Therapy Nucleic Acids 2023; 34 doi: 10.1016/j.omtn.2023.102063
25
Zheng Wang, Dan Shao, Zhimin Chang, Mengmeng Lu, Yingshuai Wang, Juan Yue, Dian Yang, Mingqiang Li, Qiaobing Xu, Wen-fei Dong. Janus Gold Nanoplatform for Synergetic Chemoradiotherapy and Computed Tomography Imaging of Hepatocellular CarcinomaACS Nano 2017; 11(12) doi: 10.1021/acsnano.7b07486
26
Jhen-Yu Chen, Yun-Ju Chen, Chia-Jui Yen, Wen-Shu Chen, Wei-Chien Huang. HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3Oncotarget 2016; 7(1) doi: 10.18632/oncotarget.6337
27
Li Wang, Yaqiong Zhan, Zhe Wu, Mengjia Lin, Xuehang Jin, Lushun Jiang, Yunqing Qiu. A novel multitarget kinase inhibitor BZG with potent anticancer activity in vitro and vivo enhances efficacy of sorafenib through PI3K pathways in hepatocellular carcinoma cellsBiomedicine & Pharmacotherapy 2020; 125 doi: 10.1016/j.biopha.2020.110033
28
Bo Zhai, Xian Jiang, Changjun He, Dali Zhao, Lixin Ma, Lishan Xu, Hongchi Jiang, Xueying Sun. Arsenic trioxide potentiates the anti-cancer activities of sorafenib against hepatocellular carcinoma by inhibiting Akt activationTumor Biology 2015; 36(4) doi: 10.1007/s13277-014-2839-3
29
Wei Dong, Kai Yan, Hua Yu, Lei Huo, Zhihong Xian, Yanqing Zhao, Jutang Li, Yuchan Zhang, Zhenying Cao, Yong Fu, Wenming Cong, Hui Dong. Prognostic Nomogram for Sorafenib Benefit in Hepatitis B Virus-Related Hepatocellular Carcinoma After Partial HepatectomyFrontiers in Oncology 2021; 10 doi: 10.3389/fonc.2020.605057
30
Su Jong Yu, Jung-Hwan Yoon. Molecular targeted therapy with transarterial chemoembolizationGastrointestinal Intervention 2013; 2(2) doi: 10.1016/j.gii.2013.09.012
31
Zhiyan Long, Xiangyi Wu, Tianxin Luo, Xiaomei Chen, Jian Huang, Shu Zhang. Exploring the Molecular Mechanism of 1,25(OH)2D3 Reversal of Sorafenib Resistance in Hepatocellular Carcinoma Based on Network Pharmacology and Experimental ValidationCurrent Issues in Molecular Biology 2025; 47(5) doi: 10.3390/cimb47050319
32
Shiyeol Jun, Soo Young Kim, Seok-Mo Kim, Ki Cheong Park, Hee Jun Kim, Ho Jin Chang, Yong Sang Lee, Hang-Seok Chang, Cheong Soo Park. Anti-cancer Activity of Paclitaxel, Lenvatinib and Radiation Combination Therapy on Anaplastic Thyroid Cancer in Vitro and in VivoKorean Society for Head and Neck Oncology 2019; 35(2) doi: 10.21593/kjhno/2019.35.2.19
33
Adel H. Jebar, Richard G. Vile, Alan A. Melcher, Stephen Griffin, Peter J. Selby, Fiona Errington-Mais. Progress in clinical oncolytic virus-based therapy for hepatocellular carcinomaJournal of General Virology 2015; 96(7) doi: 10.1099/vir.0.000098
34
Fei Long, Chengyong Dong, Keqiu Jiang, Yakun Xu, Xinming Chi, Deguang Sun, Rui Liang, Zhenming Gao, Shujuan Shao, Liming Wang. Melatonin enhances the anti-tumor effect of sorafenib via AKT/p27-mediated cell cycle arrest in hepatocarcinoma cell linesRSC Advances 2017; 7(34) doi: 10.1039/C7RA02113E
35
Zhengguang Zhang, Cunsi Shen, Fuqiong Zhou. The natural medicinal fungus Huaier promotes the anti-hepatoma efficacy of sorafenib through the mammalian target of rapamycin-mediated autophagic cell deathMedical Oncology 2022; 39(12) doi: 10.1007/s12032-022-01797-7
36
Weidong Jin, Lei Chen, Xun Cai, Yunxiao Zhang, Jianxin Zhang, Dangdang Ma, Xiong Cai, Tao Fu, Zhengping Yu, Fuxiang Yu, Gang Chen. Long non-coding RNA TUC338 is functionally involved in sorafenib-sensitized hepatocarcinoma cells by targeting RASAL1Oncology Reports 2017; 37(1) doi: 10.3892/or.2016.5248
37
Jung-Chen Su, Ping-Hui Tseng, Szu-Hsien Wu, Cheng-Yi Hsu, Wei-Tien Tai, Yong-Shi Li, I-Ting Chen, Chun-Yu Liu, Kuen-Feng Chen, Chung-Wai Shiau. SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular CarcinomaNeoplasia 2014; 16(7) doi: 10.1016/j.neo.2014.06.005
38
Keith I. Block, Charlotte Gyllenhaal, Leroy Lowe, Amedeo Amedei, A.R.M. Ruhul Amin, Amr Amin, Katia Aquilano, Jack Arbiser, Alexandra Arreola, Alla Arzumanyan, S. Salman Ashraf, Asfar S. Azmi, Fabian Benencia, Dipita Bhakta, Alan Bilsland, Anupam Bishayee, Stacy W. Blain, Penny B. Block, Chandra S. Boosani, Thomas E. Carey, Amancio Carnero, Marianeve Carotenuto, Stephanie C. Casey, Mrinmay Chakrabarti, Rupesh Chaturvedi, Georgia Zhuo Chen, Helen Chen, Sophie Chen, Yi Charlie Chen, Beom K. Choi, Maria Rosa Ciriolo, Helen M. Coley, Andrew R. Collins, Marisa Connell, Sarah Crawford, Colleen S. Curran, Charlotta Dabrosin, Giovanna Damia, Santanu Dasgupta, Ralph J. DeBerardinis, William K. Decker, Punita Dhawan, Anna Mae E. Diehl, Jin-Tang Dong, Q. Ping Dou, Janice E. Drew, Eyad Elkord, Bassel El-Rayes, Mark A. Feitelson, Dean W. Felsher, Lynnette R. Ferguson, Carmela Fimognari, Gary L. Firestone, Christian Frezza, Hiromasa Fujii, Mark M. Fuster, Daniele Generali, Alexandros G. Georgakilas, Frank Gieseler, Michael Gilbertson, Michelle F. Green, Brendan Grue, Gunjan Guha, Dorota Halicka, William G. Helferich, Petr Heneberg, Patricia Hentosh, Matthew D. Hirschey, Lorne J. Hofseth, Randall F. Holcombe, Kanya Honoki, Hsue-Yin Hsu, Gloria S. Huang, Lasse D. Jensen, Wen G. Jiang, Lee W. Jones, Phillip A. Karpowicz, W. Nicol Keith, Sid P. Kerkar, Gazala N. Khan, Mahin Khatami, Young H. Ko, Omer Kucuk, Rob J. Kulathinal, Nagi B. Kumar, Byoung S. Kwon, Anne Le, Michael A. Lea, Ho-Young Lee, Terry Lichtor, Liang-Tzung Lin, Jason W. Locasale, Bal L. Lokeshwar, Valter D. Longo, Costas A. Lyssiotis, Karen L. MacKenzie, Meenakshi Malhotra, Maria Marino, Maria L. Martinez-Chantar, Ander Matheu, Christopher Maxwell, Eoin McDonnell, Alan K. Meeker, Mahya Mehrmohamadi, Kapil Mehta, Gregory A. Michelotti, Ramzi M. Mohammad, Sulma I. Mohammed, D. James Morre, Vinayak Muralidhar, Irfana Muqbil, Michael P. Murphy, Ganji Purnachandra Nagaraju, Rita Nahta, Elena Niccolai, Somaira Nowsheen, Carolina Panis, Francesco Pantano, Virginia R. Parslow, Graham Pawelec, Peter L. Pedersen, Brad Poore, Deepak Poudyal, Satya Prakash, Mark Prince, Lizzia Raffaghello, Jeffrey C. Rathmell, W. Kimryn Rathmell, Swapan K. Ray, Jörg Reichrath, Sarallah Rezazadeh, Domenico Ribatti, Luigi Ricciardiello, R. Brooks Robey, Francis Rodier, H.P. Vasantha Rupasinghe, Gian Luigi Russo, Elizabeth P. Ryan, Abbas K. Samadi, Isidro Sanchez-Garcia, Andrew J. Sanders, Daniele Santini, Malancha Sarkar, Tetsuro Sasada, Neeraj K. Saxena, Rodney E. Shackelford, H.M.C. Shantha Kumara, Dipali Sharma, Dong M. Shin, David Sidransky, Markus David Siegelin, Emanuela Signori, Neetu Singh, Sharanya Sivanand, Daniel Sliva, Carl Smythe, Carmela Spagnuolo, Diana M. Stafforini, John Stagg, Pochi R. Subbarayan, Tabetha Sundin, Wamidh H. Talib, Sarah K. Thompson, Phuoc T. Tran, Hendrik Ungefroren, Matthew G. Vander Heiden, Vasundara Venkateswaran, Dass S. Vinay, Panagiotis J. Vlachostergios, Zongwei Wang, Kathryn E. Wellen, Richard L. Whelan, Eddy S. Yang, Huanjie Yang, Xujuan Yang, Paul Yaswen, Clement Yedjou, Xin Yin, Jiyue Zhu, Massimo Zollo. Designing a broad-spectrum integrative approach for cancer prevention and treatmentSeminars in Cancer Biology 2015; 35 doi: 10.1016/j.semcancer.2015.09.007
39
Jia-Ru Wu, Chi-Tan Hu, Ren-In You, Pei-Ling Ma, Siou-Mei Pan, Ming-Che Lee, Wen-Sheng Wu, Diego Calvisi. Preclinical Trials for Prevention of Tumor Progression of Hepatocellular Carcinoma by LZ-8 Targeting c-Met Dependent and Independent PathwaysPLOS ONE 2015; 10(1) doi: 10.1371/journal.pone.0114495
40
Ting Sun, Wenhao Mao, Hui Peng, Qi Wang, Lin Jiao. YAP promotes sorafenib resistance in hepatocellular carcinoma by upregulating survivinCellular Oncology 2021; 44(3) doi: 10.1007/s13402-021-00595-z
41
Carol Lai-Hung Cheng, Felice Hoi-Ching Tsang, Lai Wei, Mengnuo Chen, Don Wai-Ching Chin, Jialing Shen, Cheuk-Ting Law, Derek Lee, Carmen Chak-Lui Wong, Irene Oi-Lin Ng, Chun-Ming Wong. Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancerCommunications Biology 2021; 4(1) doi: 10.1038/s42003-021-02405-6
42
Zhouyang Cheng, Qingfeng Ni, Lei Qin, Yang Shi. MicroRNA-92b augments sorafenib resistance in hepatocellular carcinoma via targeting PTEN to activate PI3K/AKT/mTOR signalingBrazilian Journal of Medical and Biological Research 2021; 54(9) doi: 10.1590/1414-431x2020e10390
43
Wei Meng, Tao Chen. Association between the HGF/c‑MET signaling pathway and tumorigenesis, progression and prognosis of hepatocellular carcinoma (Review)Oncology Reports 2021; 46(3) doi: 10.3892/or.2021.8142
44
Xiangbing Meng, Eric Devor, Shujie Yang, Brandon Schickling, Kimberly Leslie. Role of MTDH, FOXM1 and microRNAs in Drug Resistance in Hepatocellular CarcinomaDiseases 2014; 2(3) doi: 10.3390/diseases2030209
45
Deniz Cansen Kahraman, Tamer Kahraman, Rengul Cetin-Atalay. Targeting PI3K/Akt/mTOR Pathway Identifies Differential Expression and Functional Role of IL8 in Liver Cancer Stem Cell EnrichmentMolecular Cancer Therapeutics 2019; 18(11) doi: 10.1158/1535-7163.MCT-19-0004
46
Lei Zhong, Xiao-Yu Fu, Chan Zou, Ling-Ling Yang, Shu Zhou, Jiao Yang, Yun Tang, Chuan Cheng, Lin-Li Li, Rong Xiang, Li-Juan Chen, Yu-Zong Chen, Yu-Quan Wei, Sheng-Yong Yang. A preclinical evaluation of a novel multikinase inhibitor, SKLB-329, as a therapeutic agent against hepatocellular carcinomaInternational Journal of Cancer 2014; 135(12) doi: 10.1002/ijc.28944
47
Expression and Function Analysis of Mitotic Checkpoint Genes Identifies TTK as a Potential Therapeutic Target for Human Hepatocellular CarcinomaPLoS ONE 2014; 9(6) doi: 10.1371/journal.pone.0097739
48
Zhongyan Zhang, Hailiang Wang, Qian Yan, Jinwei Cui, Yubin Chen, Shiye Ruan, Jiayu Yang, Zelong Wu, Mingqian Han, Shanzhou Huang, Qi Zhou, Chuanzhao Zhang, Baohua Hou. Genome-wide CRISPR/Cas9 screening for drug resistance in tumorsFrontiers in Pharmacology 2023; 14 doi: 10.3389/fphar.2023.1284610
49
FUHAI WANG, XIAOFENG DONG, PENG XIU, JINGTAO ZHONG, HONGLONG WEI, ZONGZHEN XU, TAO LI, FENG LIU, XUEYING SUN, JIE LI. T7 peptide inhibits angiogenesis via downregulation of angiopoietin-2 and autophagyOncology Reports 2015; 33(2) doi: 10.3892/or.2014.3653
50
Mingzhu Tang, Zhe Chen, Di Wu, Linxi Chen. Ferritinophagy/ferroptosis: Iron‐related newcomers in human diseasesJournal of Cellular Physiology 2018; 233(12) doi: 10.1002/jcp.26954
51
Deok Seo, Ji Park, Hee Jung, Min Kang, Byung Kang, Dong Lee, Jae Lee, Seung Yoon, Jeong Jang, Jae Ahn, Pil Sung. Machine learning model reveals roles of interferon‑stimulated genes in sorafenib‑resistant liver cancerOncology Letters 2024; 28(3) doi: 10.3892/ol.2024.14571
52
Kai-Wen Chen, Tzu-Ming Ou, Chin-Wen Hsu, Chi-Ting Horng, Ching-Chang Lee, Yuh-Yuan Tsai, Chi-Chang Tsai, Yi-Sheng Liou, Chen-Chieh Yang, Chao-Wen Hsueh, Wu-Hsien Kuo. Current systemic treatment of hepatocellular carcinoma: A review of the literatureWorld Journal of Hepatology 2015; 7(10): 1412-1420 doi: 10.4254/wjh.v7.i10.1412
53
Carolina Méndez-Blanco, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, José L. Mauriz. Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factorsExperimental & Molecular Medicine 2018; 50(10) doi: 10.1038/s12276-018-0159-1
54
Kelly Goulart Lima, Gabriele Catyana Krause, Elisa Feller Gonçalves da Silva, Léder Leal Xavier, Léo Anderson Meira Martins, Laura Manzoli Alice, Luiza Bueno da Luz, Rodrigo Benedetti Gassen, Eduardo Cremonese Filippi-Chiela, Gabriela Viegas Haute, Maria Claudia Rosa Garcia, Giselle Afonso Funchal, Leonardo Pedrazza, Camille Kirinus Reghelin, Jarbas Rodrigues de Oliveira. Octyl gallate reduces ATP levels and Ki67 expression leading HepG2 cells to cell cycle arrest and mitochondria-mediated apoptosisToxicology in Vitro 2018; 48 doi: 10.1016/j.tiv.2017.12.017
55
Sheng Li, Lina Wu, Hong Zhang, Xijuan Liu, Zilei Wang, Bin Dong, Guang Cao. GINS1 Induced Sorafenib Resistance by Promoting Cancer Stem Properties in Human Hepatocellular Cancer CellsFrontiers in Cell and Developmental Biology 2021; 9 doi: 10.3389/fcell.2021.711894
56
Rosa Maria Iacobazzi, Fabio Vischio, Ilaria Arduino, Fabio Canepa, Valentino Laquintana, Maria Notarnicola, Maria Principia Scavo, Giusy Bianco, Elisabetta Fanizza, Angela Assunta Lopedota, Annalisa Cutrignelli, Antonio Lopalco, Amalia Azzariti, Maria Lucia Curri, Massimo Franco, Gianluigi Giannelli, Byung Chul Lee, Nicoletta Depalo, Nunzio Denora. Magnetic implants in vivo guiding sorafenib liver delivery by superparamagnetic solid lipid nanoparticlesJournal of Colloid and Interface Science 2022; 608 doi: 10.1016/j.jcis.2021.09.174
57
Yixiao Sun, Xueran Guan, Ting Zhang, Yue Li, Huiling Shi, Ashleigh Tinotenda Chitakunye, Hanyu Hong, Shihui Zhang, Qin Zhu, Lin Cai. Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagyMedical Oncology 2022; 39(11) doi: 10.1007/s12032-022-01767-z
58
Supritha G. Swamy, Vivek H. Kameshwar, Priya B. Shubha, Chung Yeng Looi, Muthu K. Shanmugam, Frank Arfuso, Arunasalam Dharmarajan, Gautam Sethi, Nanjunda Swamy Shivananju, Anupam Bishayee. Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinomaTargeted Oncology 2017; 12(1) doi: 10.1007/s11523-016-0452-7
59
Fat-Moon Suk, Chao-Lien Liu, Ming-Hua Hsu, Yu-Ting Chuang, Jack P. Wang, Yi-Jen Liao. Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinomaScientific Reports 2019; 9(1) doi: 10.1038/s41598-019-53863-2
60
Junhui Sui, Yani Cui, Hanxu Cai, Shaoquan Bian, Zhiyi Xu, Ling Zhou, Yong Sun, Jie Liang, Yujiang Fan, Xingdong Zhang. Synergistic chemotherapeutic effect of sorafenib-loaded pullulan-Dox conjugate nanoparticles against murine breast carcinomaNanoscale 2017; 9(8) doi: 10.1039/C6NR09639E
61
Nikhil Kumar Chourasiya, Firdous Fatima, Mitali Mishra, Shivam Kori, Ratnesh Das, Varsha Kashaw, Arun K. Iyer, Sushil Kumar Kashaw. Structural Insights into N-heterocyclic Moieties as an Anticancer Agent against Hepatocellular Carcinoma: An Exhaustive PerspectiveMini-Reviews in Medicinal Chemistry 2023; 23(19) doi: 10.2174/1389557523666230508160924
62
Victoria Foy, Mairéad G. McNamara, Juan W. Valle, Angela Lamarca, Julien Edeline, Richard A. Hubner. Current Evidence for Immune Checkpoint Inhibition in Advanced Hepatocellular CarcinomaCurrent Oncology 2023; 30(9) doi: 10.3390/curroncol30090628
63
Sónia R. Veiga, Xuemei Ge, Carol A. Mercer, María I. Hernández-Álvarez, Hala Elnakat Thomas, Javier Hernandez-Losa, Santiago Ramón y Cajal, Antonio Zorzano, George Thomas, Sara C. Kozma. Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTORClinical Cancer Research 2018; 24(15) doi: 10.1158/1078-0432.CCR-18-0177
64
Chen Huang, Yangqian Li, Fengmei Zhang, Chenliang Zhang, Zhenyu Ding. Advancements in elucidating the mechanisms of Sorafenib resistance in hepatocellular carcinomaInternational Journal of Surgery 2025; 111(4) doi: 10.1097/JS9.0000000000002294
65
Sandeep Kumar Vishwakarma, Priyanka Sharmila, Avinash Bardia, Lakkireddy Chandrakala, N. Raju, G. Sravani, B. V. S. Sastry, Md Aejaz Habeeb, Aleem Ahmed Khan, Marshal Dhayal. Use of Biocompatible Sorafenib-gold Nanoconjugates for Reversal of Drug Resistance in Human Hepatoblatoma CellsScientific Reports 2017; 7(1) doi: 10.1038/s41598-017-08878-y
66
Xue-Mei Jiang, Xiang-Nan Yu, Tao-Tao Liu, Hai-Rong Zhu, Xuan Shi, Enkhnaran Bilegsaikhan, Hong-Ying Guo, Guang-Qi Song, Shu-Qiang Weng, Xiao-Xi Huang, Ling Dong, Harry L.A. Janssen, Xi-Zhong Shen, Ji-Min Zhu. microRNA-19a-3p promotes tumor metastasis and chemoresistance through the PTEN/Akt pathway in hepatocellular carcinomaBiomedicine & Pharmacotherapy 2018; 105 doi: 10.1016/j.biopha.2018.06.097
67
Wei-De Wu, Pin-Shern Chen, Hany A. Omar, El-Shaimaa A. Arafa, Hung-Wei Pan, Jingyueh Jeng, Jui-Hsiang Hung. Antrodia cinnamomea boosts the anti-tumor activity of sorafenib in xenograft models of human hepatocellular carcinomaScientific Reports 2018; 8(1) doi: 10.1038/s41598-018-31209-8
68
Yuanpeng Bao, Song Xu, Junjing Zhou, Chongyong Zhao, Saimin Dai, Yong Zhang, Min Rao. Exosomal miR‐93 derived from hepatocellular carcinoma cell promotes the sorafenib resistance of hepatocellular carcinoma through PTEN/PI3K/Akt pathwayJournal of Biochemical and Molecular Toxicology 2024; 38(3) doi: 10.1002/jbt.23666
69
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