Clinical effects of continuous high volume hemofiltration on severe acute pancreatitis complicated with multiple organ dysfunction syndrome

Table 1 Incidence of complications before HVHF

Complications	Case	Incidence (%)
SIRS*	28	100
Systemic infection	10	35.7
ARDS*	20	71.4
Shock	14	50.0
Renal failure	7	25.0
Pancreatic encephalopathy	6	21.4
Bleeding in alimentary tract	12	42.8
Cardiac arrhythmia	4	14.3
Heart failure/pulmonary edema	2	7.1
Dysfunction of coagulation	4	14.3
Liver function failure	2	7.1
Fungal infection	7	25.0

SIRS: Systemic inflammatory response syndrome; ARDS: Acute respiratory distress syndrome.

Table 2 Changes of vital signs after HVHF

	T0	T24	T48	T72	T96	T120
Case	28	28	28	28	28	28
BT (°C)	37.8 ± 0.8	37.3 ± 0.8a	37.2 ± 0.7a	37.2 ± 0.8a	37.3 ± 0.9	37.5 ± 0.9b
HR (bpm)	127 ± 23	120 ± 30	107 ± 25a	101 ± 24a	103 ± 17a	102 ± 21a
BR (tpm)	31 ± 5	22 ± 4a	21 ± 5a	19 ± 1a	20 ± 1a	19 ± 2a
MAP(kpa)	13.8 ± 1.9	13.8 ± 2.0	14.1 ± 2.3	13.6 ± 1.7	13.5 ± 1.7	13.8 ± 1.8

^aP < 0.01, vs T₀;

^bP < 0.05, vs T₀; BT: Body temperature (°C); HR: Heart rate (beats per minute); BR: Breath rate (times per minute); MAP: Mean arterial pressure (kpa).

Table 3 Changes of laboratory parameters after HVHF

Index	Pre HVHF	Post HVHF
Case	28	28
APACHE II score	14.4 ± 3.9	9.9 ± 4.3a
PaO2	68.5 ± 19.5	91.9 ± 25a
CRP	187 ± 39	87.4 ± 112
White cell count	15.5 ± 5.8	14.9 ± 6.9
Serum amylase	392 ± 517	103 ± 184a
Blood urea nitrogen	9.9 ± 10.1	5.0 ± 2.9b
Serum albumin	33.0 ± 5.4	31.8 ± 4.8

^aP < 0.01, vs pre-HVHF;

^bP < 0.05, vs pre-HVHF.