Experimental study of effect of Ganyanping on fibrosis in rat livers

Table 1 Area occupied by fibrotic septa and its ratio to the total area examined

Groups	n	Area covered by fibrotic septa (μm2)	Ratio (%)
N	8	35.30 ± 13.86b	0.32 ± 0.18b
A	15	200.74 ± 33.84a	1.63 ± 0.45a
B	15	148.73 ± 45.89a	1.16 ± 0.33a
C	15	158.73 ± 40.89a	1.12 ± 0.28a
D	15	840.23 ± 81.65	7.00 ± 0.90

^aP < 0.05 vs Group D,

^bP < 0.001 vs Group D.

Table 2 Semiquantitative assessment of enzymatic activities in different liver samples

Groups	n	MAO	SDH	ACP	LDH	NOS	ALP
N	8	++	+++	+	++	++	++
A	15	++	+++	++	+↓	++	++
B	15	++	+++	+	++	++	++
C	15	++	+++	+	++	++	++
D	15	+++↑	++↓	+++↑	+↓	++	++

+: positive; ++: moderately positive; +++: strongly positive; ↑: activity enhancement; ↓: activity weakened.

Table 3 Quantitative observation of the liver enzymatic activities (mean absorbance)

Groups	n	MAO	SDH	ACP	LDH
N	8	0.2042 ± 0.041a	0.4057 ± 0.030a	0.1160 ± 0.0338a	0.1685 ± 0.0103
A	15	0.3201 ± 0.066a	0.2917 ± 0.045a	0.1623 ± 0.0246a	0.1948 ± 0.0319
B	15	0.3308 ± 0.079a	0.3380 ± 0.103a	0.2101 ± 0.0342a	0.1331 ± 0.0071
C	15	0.1835 ± 0.060a	0.3939 ± 0.0434a	0.1884 ± 0.0542a	0.1757 ± 0.0216
D	15	0.5022 ± 0.149	0.1819 ± 0.1049	0.4235 ± 0.0727	0.1656 ± 0.0145

^aP < 0.05 vs group D.