Loss of fragile histidine triad protein in human hepatocellular carcinoma

Table 1 Levels of Fhit expression in heptocellular carcinomas, para-neoplastic tissues and normal liver tissues

	Fhit score
	n	-	+	+ +
HCC	83	29	21	33
Para-neoplastic tissueb	83	0	0	8 3
Normal liver tissueb	10	0	0	10

^bP = 0.000, vs hepatocellular carcinomas.

Table 2 Relationship between Fhit expression and clinicopathological indice

	Fhit score
	n	-	+	++
Histological grade
Grade I	15	3	4	8
Grade II	39	12	9	18
Grade III	29	14	8	7
Clinical stage
Stage I-II	37	4	4	29
Stage III-IV	46	25	17	4
Size (mm)
≤ 50	39	10	7	22
> 50	44	19	14	11