DNA polymerase &zeta;: new insight into eukaryotic mutagenesis and mammalian embryonic development

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Jun 15, 2003 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 15, 2003; 9(6): 1165-1169
Published online Jun 15, 2003. doi: 10.3748/wjg.v9.i6.1165

Table 1 Characteristics of mRev3^-/- embryo

Size	Reduced at day 10.5
Viability	Usually aborted around day 12.5
Inner cell mass (ICM)	Diminished expansion
Haematopoietic cells	No haematopoietic cells developed other than erythrocytes
Morphogenesis of embryo	1. Abnormalities in the development and maintenance of embryonic mesoderm
	2. Predominant disorder and lack of integrity mainly in mesenchymal tissues, including heart and large blood vessels

Citation: Zhu F, Zhang M. DNA polymerase ζ: new insight into eukaryotic mutagenesis and mammalian embryonic development. World J Gastroenterol 2003; 9(6): 1165-1169
URL: https://www.wjgnet.com/1007-9327/full/v9/i6/1165.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i6.1165