Shen L, Fan JG, Shao Y, Zeng MD, Wang JR, Luo GH, Li JQ, Chen SY. Prevalence of nonalcoholic fatty liver among administrative officers in Shanghai: an epidemiological survey. World J Gastroenterol 2003; 9(5): 1106-1110 [PMID: 12717867 DOI: 10.3748/wjg.v9.i5.1106]
Corresponding Author of This Article
Dr Jian-Gao Fan, Department of Gastroenterology, First People’s Hospital, Shanghai 200080, China. fanjg@citiz.net
Article-Type of This Article
Clinical Research
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. May 15, 2003; 9(5): 1106-1110 Published online May 15, 2003. doi: 10.3748/wjg.v9.i5.1106
Table 1 Obesity indices and lipid parameters in males and females
Parameters
Male
Female
P value
BMI
23.5 ± 2.7
21.5 ± 2.6
< 0.001
WHR
0.86 ± 0.05
0.79 ± 0.06
< 0.001
TG (mg/dl)
126.3 ± 87.7
97.2 ± 75.2
< 0.001
TCh (mg/dl)
188.8 ± 56.7
189.3 ± 56.6
> 0.050
HDL-Ch (mg/dl)
81.4 ± 75.4
84.4 ± 57.0
> 0.050
LDL-Ch (mg/dl)
143.1 ± 166.0
133.5 ± 153.7
> 0.050
Table 2 Difference of prevalences of several diseases in males and females
Diseases
Male%
Female%
P value
Abnormal ALT
2.1
0.35
< 0.001
Positive HBsAg
7.3
4.8
< 0.001
Arteriosclerosis of optic fundus
13.4
6.3
< 0.001
Diabetes mellitus
5.1
3.3
< 0.001
Coronary artery disease
3.5
2.3
< 0.001
Hypertension
15.3
8.2
< 0.001
Gallstone
8.9
8.9
> 0.050
Fatty liver
15.8
7.5
< 0.001
Table 3 Relation between hyperlipidemia and age in males and females
Age(yr)
Sex
n
Hypertriglyc erinemia%
Hyperchole sterolemia%
Mixed Hyperlipide mia%
Sum%
< 30
Male
314
11.6
1.5
1.2
14.3
Female
257
1.1
2.7
0.7
4.5
Total
571
6.9
2.1
1.0
9.0
30-50
Male
1202
17.3
3.9
4.9
26.1
Female
726
4.5
4.9
1.3
10.7
Total
1928
12.5
4.3
3.6
20.3
51-64
Male
702
22.6
6.9
9.2
38.7
Female
324
16.9
18.5
17.5
52.9
Total
1026
20.8
10.6
11.8
43.2
≥ 65
Male
365
28.5
12.9
11.3
52.7
Female
119
24.2
25.0
14.3
63.5
Total
484
27.4
27.4
12.0
55.4
Table 4 Prevalence of fatty liver in groups of different sex and ages
Age(years)
Sex
Number
Fatty liver n%
< 30
Males
314
11 (6.4)
Females
257
2 (1.6)
Total
571
13 (2.3)
30-50
Males
1202
190 (20.7)
Females
726
25 (5.4)
Total
1928
215 (11.2)
51-64
Males
702
125 (17.9)
Females
324
57 (19.7)
Total
1026
182 (17.7)
≥ 65
Males
365
83 (22.7)
Females
119
23 (19.3)
Total
484
106 (21.9)
Table 5 Obesity indices and lipid parameters in groups with and without fatty liver
Age (years)
BMI (kg/m2)
WHR
TG (mg/dl)
TCh (mg/dl)
Group without fatty liver
44.6 ± 14.3
22.2 ± 2.4
0.8 ± 0.1
105.0 ± 78.4
186.2 ± 59.5
Group with fatty liver
52.3 ± 13.0
26.0 ± 2.4
0.9 ± 0.1
168.6 ± 93.4
202.2 ± 37.7
Table 6 Results of monovariant regression analysis of fatty liver and various parameters
Parameters
B value
β value
T value
P value
Sex
0.038
0.063
2.59
0.0000
Age
0.53
0.062
2.79
0.0018
BMI
0.073
0.522
23.89
0.0000
Waist circumference
0.010
0.216
5.87
0.0000
WHR
0.782
0.129
4.96
0.0000
TG
0.000
0.084
3.08
0.0021
TCh
-0.0000
-0.079
-3.12
0.0016
HDL-Ch
-0.000
-0.047
-2.17
0.0300
LDL-Ch
-0.000
0.332
2.61
0.0092
Hyperlipidemia
0.094
0.160
7.27
0.0000
Arteriosclerosis
0.062
0.087
3.59
0.0000
Hypertension
0.068
0.099
4.45
0.0000
Diabetes mellitus
0.149
0.130
3.42
0.0000
Coronary heart disease
0.142
0.067
3.14
0.0018
Abnormal ALT
0.156
0.069
3.24
0.0012
Positive HBsAg
-0.09
0.063
-3.02
0.0026
Table 7 Results of Logistic multivariant regression analysis
B
SE
Wald
df
Sig
R
Exp (B)
WHR
2.2
0.19
139.2
1
0.00
0.30
9.1
Abnormal ALT
1.3
0.26
27.0
1
0.00
0.08
3.8
BMI
0.9
0.15
35.3
1
0.00
0.15
2.4
Positive HBsAg
-0.7
0.24
9.3
1
0.00
-0.04
0.05
Hyperlipidemia
0.6
0.06
99.9
1
0.00
0.16
1.8
Diabetes mellitus
0.5
0.11
21.5
1
0.00
0.07
1.7
Hyperlipidemia
0.4
0.05
81.0
1
0.00
0.15
1.5
Sex
0.4
0.05
55.1
1
0.00
0.12
1.5
Arteriosclerosis
0.2
0.09
6.8
1
0.01
0.04
1.3
Citation: Shen L, Fan JG, Shao Y, Zeng MD, Wang JR, Luo GH, Li JQ, Chen SY. Prevalence of nonalcoholic fatty liver among administrative officers in Shanghai: an epidemiological survey. World J Gastroenterol 2003; 9(5): 1106-1110