Association of two polymorphisms of tumor necrosis factor gene with acute biliary pancreatitis

Table 1 Comparison of TNF Genotype among different groups

	TNF-308			TNFB
	G/G	G/A	A/A	1/1	1/2	2/2
ASBP	43 (70.5)	15 (24.6)	3 (4.9)	19 (31.1)	25 (41.0)	17 (27.9)
AMBP	49 (74.2)	14 (21.2)	3 (4.5)	22 (33.3)	26 (39.4)	18 (27.3)
	χ2 = 0.040, P = 0.980			χ2 = 0.197, P = 0.906
ABP	92 (72.4)	29 (22.8)	6 (4.7)	41 (32.3)	51 (40.1)	35 (27.6)
Control	76 (74.5)	21 (20.6)	5 (4.9)	39 (38.2)	35 (34.3)	28 (27.5)
	χ2 = 2.545, P = 0.280			χ2 = 3.594, P = 0.166

Note. Comparison by chi-square test. No significant differences were found in the distribution of each genotype frequency [no. (%)] between any of the two groups.

Table 2 Comparison of TNF2 frequency and TNFB2 frequency between septic shock group and no septic shock group

	Septic shock (n = 18)	No septic shock (n = 43)	P
TNF2	9 (44.4%)	9 (20.9%)	0.023
TNFB2	13 (72.2%)	29 (67.4%)	0.713

Patients with septic shock showed a significantly higher preva-lence of the TNF2 than those without. No such association was seen in TNFB2.