Copyright
©The Author(s) 2003.
World J Gastroenterol. Apr 15, 2003; 9(4): 717-720
Published online Apr 15, 2003. doi: 10.3748/wjg.v9.i4.717
Published online Apr 15, 2003. doi: 10.3748/wjg.v9.i4.717
Table 1 Patient demography and disease charateristiscs at baseline
Parameter | RCS group | RS group |
Male/female | 12/3 | 21/6 |
Age (years): median (range) | 56 (33-72) | 58 (18-71) |
Karnofsky performance status | 70-90 | 70-90 |
Primary site | ||
Middle | 4 | 7 |
lower | 11 | 20 |
Degree of differentiation | ||
Well | 1 | 2 |
Moderate | 7 | 15 |
Poor | 3 | 4 |
Not specified | 4 | 6 |
TNM staging | ||
T3N0M0 | 5 | 14 |
T3N1M0 | 0 | 3 |
T4N0M0 | 6 | 3 |
T4N1M0 | 4 | 5 |
T4N2M0 | 0 | 2 |
Table 2 The radical resectability, sphincter preservation, lower rectal cancer sphincter preservation, response and tumor down-stage rates in the two groups
Parameter | RCS group | RS group | P |
Radical resectability rate | 73.3% | 37.0% | 0.024 |
Sphincter preservation rate | 26.6% | 3.7% | 0.028 |
Lower rectal cancer sphincter | 27.3% | 0.0% | 0.014 |
preservation rate | |||
Response rate | 46.7% | 18.5% | 0.053 |
Tumor downstage rate | 53.3% | 33.3% | 0.206 |
Table 3 The 3-year overall survival, disease free survival and local recurrent rates of the patients of two groups
Parameter | RCS group | RS group | P |
3-year overall survival rate | 66.7% | 55.6% | 0.485 |
3-year disease free survival rate | 40.1% | 33.2% | 0.663 |
3-year local recurrent rate | 26.7% | 48.1% | 0.174 |
Table 4 WHO modified scale for acute toxicity
Site | Grading (RCS group) | Grading (RS group) | ||||||||
0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 | |
Hematologic: | ||||||||||
Neutropenia | 8 | 2 | 4 | 1 | 0 | 19 | 3 | 5 | 0 | 0 |
Non-hematologic: | ||||||||||
Small bowl | 4 | 3 | 7 | 3 | 0 | 6 | 9 | 10 | 2 | 0 |
Bladder | 6 | 4 | 5 | 0 | 0 | 10 | 11 | 6 | 0 | 0 |
Skin | 0 | 2 | 6 | 7 | 0 | 0 | 10 | 8 | 9 | 0 |
- Citation: Sun XN, Yang QC, Hu JB. Pre-operative radiochemotherapy of locally advanced rectal cancer. World J Gastroenterol 2003; 9(4): 717-720
- URL: https://www.wjgnet.com/1007-9327/full/v9/i4/717.htm
- DOI: https://dx.doi.org/10.3748/wjg.v9.i4.717