Expression of cyclooxygenase-2 and clinicopathologic features in human gastric adenocarcinoma

Table 1 Clinicopathologic features in these patiens and COX-2 index (^-x ± s)

Parameter	-x ± s	P
Sex
male (n = 27)	0.5798 ± 0.2754	NSa
female (n = 6)	0.6722 ± 0.2012
Age (range)
≤ 60 (n = 16)	0.6144 ± 0.2655	NS
> 60 (n = 17)	0.5799 ± 0.2651
Blood group
A type (n = 10)	0.5928 ± 0.2647	NS
B type (n = 11)	0.6415 ± 0.264
O type (n = 7)	0.5906 ± 0.2614
AB type (n = 5)	0.6221 ± 0.2551
Greatest tumor dimension
< 5 cm (n = 11)	0.4929 ± 0.2807	NS
≥ 5 cm (n = 22)	0.6485 ± 0.242
Histopathologic type
Middling differentiation (n = 7)	0.5772 ± 0.2645	NS
Low differentiation (n = 9)	0.5563 ± 0.249
Middling and low differentiation (n = 6)	0.4278 ± 0.2911
Signet-ring/mucous cell (n = 11)	0.7341 ± 0.186
Gross type
Borrmann I (n = 8)	0.4897 ± 0.28	NS
Borrmann II III (n = 22)	0.6244 ± 0.2672
Borrmann IV (n = 3)	0.6785 ± 0.0443
Depth of invasionb
pT2 (n = 10)	0.5198 ± 0.2516	NS
pT3 (n = 11)	0.5682 ± 0.2526
pT4 (n = 12)	0.686 ± 0.2633
Lymph nodeb
pN0 (n = 10)	0.4105 ± 0.2182	< 0.05
pN1 and pN2 (n = 23)	0.6775 ± 0.2486
TNM stageb
I and II (n = 9)	0.4054 ± 0.2275	< 0.05
III (n = 13)	0.6561 ± 0.2233
IV (n = 11)	0.6829 ± 0.2631
Tumor location
Antrum (n = 18)	0.5678 ± 0.314	NS
Corpus (n = 6)	0.6771 ± 0.1488
Cardiac orifice (n = 9)	0.6006 ± 0.203

^aNS, not significant.

^bEach factor of pT, pN and TNM stage was determined according to the UICC TNM classification, published in 1985.