Clinical predictors of severe gallbladder complications in acute acalculous cholecystitis

Table 1 Predisposing factors in patients with acute acalculous cholecystitis

Predisposing factor	Total (n)
Shock	7
Trauma	2
Burn	1
Major surgery	2
Bacteremia	11
DM	8
HTN	13
Heart diseasea	14
CVA	3
TPN	1
Hyperlipidemia	5

a: Heart disease includes atrial fibrillation, congestive heart failure, hypertensive cardiovascular disease, hypertrophic car-diomyopathy and dilated cardiomyopathy.

Table 2 Demographic and clinical data in patients with acute acalculous cholecystitis with and without severe complications

	Group A n = 27	Group B n = 25	P
Gender
Female	8	7	0.28
Male	19	18	0.71
Age (years)	60.88	54.12	0.04
Hospital stay (days)	19.74	18.84	0.42
WBC/mm3	15 885.19	9 948.40	0.0005
AST (u/l)	138.04	141.87	0.48
Bilirubin (mg/dl)	2.46	2.37	0.46
Alkaline phosphatase (u/l)	106.19	130.59	0.07
Gallbladder wall (mm)	8.8	8.55	0.38

Table 3 Results of blood and bile culture for bacteria in pa-tients with acute acalculous cholecystitis

Culture	Blood (n)	Bile (n)
No growth	34 (76%)	14 (34%)
Bacteria(+)	11 (24%)	27 (66%)

Table 4 Bacteria cultured from blood in patients with acute acalculous cholecystitis

	Group A (n)	Group B (n)	Total (n)
E.coli	3	3	6
Klebsiella pneumoniae	1	2	3
Aeromonas sp	0	1	1
Salmonella gr.D	1	0	1
G(+) Bacilli	1	0	1

Table 5 Bacteria cultured from bile in patients with acute acalculous cholecystitis

	Group A (n)	Group B (n)	Total (n)
E.coli	12	1	13
Klebsiella pneumoniae	6	1	7
Aeromonas	0	1	1
Salmonella gr.D	1	1	2
Enterobacter sp.	2	0	2
Pseudomonas sp.	1	1	2
Burkholderia cepacia	1	0	1
Candida albican	0	1	1
Citro. Freundii	1	0	1
Enterococcus	1	0	1
Providencia	0	1	1
Stophy. Coagulase (-)	1	0	1

Table 6 Sonographic findings recorded including gallbladder thickening, distention, and sludge

Sonographic finding	1 point	2 points	3 points	Total
Group A	4	11	9	24
Group B	9	11	4	24
Subtotal	13	22	13	48
χ2 = 3.85	P > 0.05