Seroreactivity against Saccharomyces cerevisiae in patients with Crohn’s disease and celiac disease

Table 1 ASCA positive patients in different diseases of bowels

	ASCA IgG+	ASCA IgA+	ASCA IgG+IgA+	IgG vs IgA corr.(r)
All patients (n = 68)	5	4	10	0.75
Crohn’s disease (n = 42)	1	2	8	0.81
Ulcerative colitis (n = 10)	2	1	0	-0.01
Celiac disease (n = 16)	2	1	2	0.50
Controls (n = 20)	0	0	0	-0.18

Notes: It is clear that there was no ASCA positivity in the controls. ASCA positivity was common in patients with Crohn’s disease. The ASCA IgG- and IgA-type seropositivity was concomitant.

Table 2 ASCA positive patients with different forms of Crohn’s disease

Affected section of the bowels	ASCA IgG+	ASCA IgA+	ASCA IgG+IgA+
Only the colon (n = 27)	1	0	0
Large and small bowels both (n = 8)	0	0	4
Only small bowels (n = 7)	0	2	4
Small bowel together (n = 15)	0	2	8

Notes: Both the IgA and IgG type ASCA associated to the small bowels. P < 0.0004, ASCA IgG+ vs small bowels; P < 0.0001 ASCA IgA+ vs small bowels.

Table 3 Summary of ASCA positive cases with Crohn’s disease

Case:	ASCA IgG	ASCA IgA	ASCA IgG+IgA	Age (years)	Sex	Affected sections of gastrointestinal tract
1.		+		19	Female	Terminal ileum
2.			+	46	Male	Terminal ileum
3.			+	37	Male	Terminal ileum
4.			+	38	Female	Terminal ileum
5.	+			50	Female	Colon
6.			+	29	Male	From the duodenum to the rectum
7.		+		40	Female	Terminal ileum
8.			+	24	Male	Terminal ileum + colon
9.			+	49	Female	From the duodenum to the rectum
10.			+	41	Female	Terminal ileum
11.			+	27	Male	Terminal ileum + colon