Analysis for phenotype of HNPCC in China

Table 1 Clinical data of 54 probands

Parameters	ICG-HNPCC	sHNPCC	Total	Sporadic CRC
Sex male	6 (50%)	14 (33.3%)	20 (37%)	319 (43%)
female	6 (50%)	28 (66.7%)	34 (63.0%)	423 (57%)
Mean age	39 y	47.5 y	45.7 y	56 y
tumor site colon	9 (75.0%)	26 (62.0%)	35 (64.8%)	226 (30.5%)
rectum	3 (25.0%)	16 (38.0%)	19 (35.2%)	516 (69.5%)
Dukes' stage A+B	7 (58.3%)	34 (81.0%)	41 (75.9%)	347 (47.8%)
C+D	5 (41.7%)	8 (19.0%)	13 (24.1%)	380 (52.2%)
Differentiation high	6 (54.5%)	12 (30.8%)	18 (36.0%)	89 (15.3%)
moderate	5 (45.5%)	22 (56.4%)	27 (54.0%)	397 (68.1%)
poorly	0	5 (12.8%)	5 (10.0%)	97 (16.6%)
Pathology mucinous tumors	1 (8.3%)	9 (21.4%)	10 (18.5%)	159 (21.4%)
Non-mucinous tumors	11 (91.7%)	33 (78.6%)	44 (81.5%)	583 (78.6%)
Multiple CRCs	2 (16.7%)	6 (14.3%)	8 (14.8%)	25 (3.4%)