Inhibition of human telomerase in MKN-45 cell line by antisense hTR expression vector induces cell apoptosis and growth arrest

Table 1 Comparison of distribution of cell cycle, cellular proliferation index, apoptotic rate, population doubling time of MKN-45-ahTR and those of control cells

	Distribution of cell cycle (%)			cell proliferationindex (%)	Apoptotic rate (%)	population doubling time (hours)
	G0/G1	S	G2/M
MKN-45-ahTR	65	34.2	0.8	35	25.3	35.3
MKN-45-hTR	55.7	37.5	6.8	44.3	0	23.2
MKN-45-empty	54.1	38.4	7.5	45.9	0	22.7
normal MKN-45	54.7	37.8	7.5	45.3	0	22.9