Prediction of recurrence and prognosis in patients with hepatocellular carcinoma after resection by use of CLIP score

Table 1 CLIP score system

Variable	Scores
	0	1	2
Child-Pugh stage	A	B	C
Tumor morphology	Uninodular and extension ≤ 50%	Multinodular and extension ≤ 50%	Massive or extension > 50%
AFP (ng/Dl)	< 400	≥ 400
Portal vein thrombosis	No	Yes

Table 2 Characteristics of host-and treatment-related factors in patients with HCC after resection

Characteristics	Early recurrence (n = 109)	Late recurrence (n = 16)	No recurrence (n = 28)
Age	50.7 ± 9.8	49.2 ± 8.5	48.3 ± 10.2
Gander (M/F)	100/9	13/3	24/4
HbsAg
positive	78	12	18
negative	31	4	10
Tumor family history
Yes	16	5	4
No	91	11	24
Unknown	2	0	0
Cirrhosis
Yes	82	12	18
No	27	4	10
Child-Pugh
A	91	10	26
B	31	6	2
C	1	0	0
Preoperative TAE
Yes	18	0	4
No	97	16	24
splenectomy
Yes	11	1	4
No	98	15	24
Resection margin (cm)
< 1	67	4	4
≥ 1	42	12	24
Postoperative chemotherapy
Yes	58	9	13
No	51	7	15

Table 3 Characteristics of tumor-related factors in patients with HCC after resection

Characteristics	Early recurrence (n = 109)	Late recurrence (n = 16)	No recurrence (n = 28)
Serum AFP ( μg•L⁻¹)
< 400	66	8	14
≥ 400	43	8	14
Tumor size/cm
≤ 5	43*	7	21
> 5	66	9	7
Microsatellite
Absent	69	14	28
present	40	2	0
Venous invasion
Absent	78	15	28
present	31	1	0
Tumor type
Uninodular	78	14	27
Multinodular	17	2	1
Massive	14	0	0
Tumor extension
≤ 50%	90	15	28
> 50%	19	1	0
UICC TNM stage
I	1	1	9
II	36	11	18
III	51	12	1
IV	21	2	0
CLIP scores
0	21	6	11
1	38	3	15
2	25	6	1
3	4	0	1
4-5	11	1	0