Association of H. pylori infection with gastric carcinoma: A meta analysis

Table 1 Eleven case-control studies of H. pylori vs. gastric cancer[21-31]

No.	Cases		Controls		OR	95%CI	χ²	P value
	Hp (+)	Hp (-)	Hp (+)	Hp (-)
1	61	13	49	25	2.394	1.110～5.163	4.284	0.038
2	13	3	78	68	3.778	1.033～13.818	3.475	0.062
3	71	21	46	46	3.381	1.791～6.384	13.52	0.000
4	99	23	6	8	5.793	1.841～18.155	8.400	0.004
5	35	16	34	87	5.597	2.746～11.408	22.873	0.000
6	101	35	6236	4628	2.142	1.455～3.151	14.959	0.000
7*	16	9	32	43	2.389	0.937～6.092	2.618	0.106
8*	21	19	3	12	4.421	1.080～18.093	3.457	0.063
9*	55	21	12	10	2.183	0.821～5.805	1.75	0.186
10	90	13	89	50	3.889	1.977～7.653	15.500	0.000
11	60	25	35	50	3.429	1.815～6.475	13.743	0.000
Summary	622	198	6620	5027	3.0016	2.4197～3.7234	99.9483	0.000

^*the literatures that did not attain significant results.

Table 2 Seven case-control studies of H. pylori vs. precancerous lesion of stomach[32-38]

No.	Cases		Controls		OR	95%CI	χ²	P value
	Hp (+)	Hp (-)	Hp (+)	Hp (-)
1	344	194	1467	1311	1.585	1.309～1.918	22.089	0.000
2	67	29	175	180	2.376	1.466～3.851	11.955	0.000
3	103	38	26	53	5.525	3.036～10.056	31.988	0.000
4	427	252	992	892	1.524	1.273～1.824	20.736	0.000
5	99	41	12	28	5.634	2.614～12.144	20.128	0.000
6	134	35	272	201	2.829	1.870～4.282	24.490	0.000
7	188	27	332	135	2.831	1.805～4.442	20.836	0.000
Summary	1362	616	3276	2800	2.5635	1.8477～3.5566	31.7540	0.000

Table 3 Three case-control studies of H. pylori vs. lymphoma of stomach[39-41]

No.	Cases		Controls		OR	95%CI	χ²	P value
	Hp (+)	Hp (-)	Hp (+)	Hp (-)
1	24	5	13	16	5.908	1.762～19.810	7.465	0.006
2	15	0	36	24	10.811	1.347～86.798	5.692	0.017
3	34	5	31	23	5.045	1.709～14.896	8.176	0.004