Treatment of rotaviral gastroenteritis with Qiwei Baizhu powder

Table 1 The curative effect of QWBZP and ORS

Group	Total cases	Cured cases	Efficient cases	Inefficient cases
ORS	72	45	15	12
QWBZP	83	71	8	4

Table 2 Changes of electrolytes in serum and hematocrit after treatment (mean ± SD)

Treatment	Cases	Time point	Na+ (mmol/L)	K+ (mmol/L)	Cl- (mmol/L)	Hematocrit (%)
ORS	72	Before treatment	146.4 ± 9.4	3.9 ± 0.2	98.5 ± 5.0	50.6 ± 4.6
		After treatment	140.6 ± 7.3a	4.1 ± 0.3	102.4 ± 6.7	45.7 ± 3.8a
QWBZP	83	Before treatment	145.7 ± 8.6	3.8 ± 0.2	101.0 ± 5.4	51.2 ± 4.4
		After treatment	141.2 ± 8.1a	3.9 ± 0.3	103.5 ± 4.8	46.1 ± 5.8a

^aP ＜ 0.05 vs the same group before treatment.

Table 3 Changes of sodium and glucose in stool after treatment (mmol/L, mean ± SD)

Treatment	Cases	Time point	Sodium	Potassium	Chloride	glucose
ORS	72	Before treatment	25.3 ± 4.1	18.5 ± 3.4	11.7 ± 2.6	0.9 ± 0.2
		After treatment	26.8 ± 4.7	11.7 ± 4.1	13.0 ± 3.1	1.0 ± 0.4
QWBZP	83	Before treatment	26.2 ± 4.3	17.3 ± 3.5	12.4 ± 2.5	0.9 ± 0.3
		After treatment	11.5 ± 3.6ab	10.4 ± 2.8ab	6.8 ± 2.7ab	0.2 ± 0.1ab

^aP ＜ 0.05 vs the same group before treatment;

^bP ＜ 0.05 vs ORS group.

Table 4 Changes of body weight of mice after inoculation (g, mean ± SD)

Group	n	Days post-inoculation
		1 d	4 d	7 d
Normal	4	2.2 ± 0.2	2.8 ± 0.4	5.1 ± 0.6
Infected	5	2.1 ± 0.3	2.2 ± 0.2	2.3 ± 0.4
ORS	5	2.2 ± 0.2	2.4 ± 0.3	3.6 ± 0.5a
QWBZP	6	2.1 ± 0.3	2.7 ± 0.4a	4.8 ± 0.5b

^aP ＜ 0.05,

^bP ＜ 0.01 vs infected group.

Table 5 Changes of content of fecal sodium (mmol/L, mean ± SD)

Group	n	Days post-inoculation
		1 d	4 d	7 d
Normal	4	9.5 ± 0.6	10.2 ± 0.8	9.3 ± 1.2
Infected	5	10.1 ± 1.1	22.9 ± 2.2ab	24.7 ± 1.9ab
ORS	5	9.7 ± 0.9	26.5 ± 1.3ab	15.7 ± 1.9cd
QWBZP	6	10.4 ± 1.1	11.6 ± 1.4	11.2 ± 1.1

^aP ＜ 0.001,

^bP ＜ 0.01 vs QWBZP group.

^cP ＜ 0. 001,

^dP ＜ 0.01 vs the same group before treatment.

Table 6 Changes of content of glucos in stool (mmol/L, mean ± SD)

Group	n	Days post-inoculation
		1 d	4 d	7 d
Normal	4	0.1 ± 0.2	0	0.1 ± 0.1
Infected	5	0	1.1 ± 0.3a	1.3 ± 0.4a
ORS	5	0	1.2 ± 0.4a	1.2 ± 0.3a
QWBZP	6	0.1 ± 0.1	0.2 ± 0.2	0.1 ± 0.1

^aP ＜ 0.01 vs QWBZP group.

Table 7 Changes of content of glucos in serum (mmol/L, mean ± SD)

Group	n	Days post-inoculation
		1 d	4 d	7 d
Normal	4	4.4 ± 1.2	3.9 ± 1.4	4.1 ± 1.2
Infected	5	4.2 ± 0.9	3.8 ± 1.3	4.3 ± 0.9
ORS	5	4.4 ± 0.8	4.6 ± 1.4	4.5 ± 1.7
QWBZP	6	4.1 ± 1.6	4.5 ± 1.5	4.8 ± 1.6

Table 8 Changes of content of serous sodium (mmol/L, mean ± SD)

Group	n	Days post-inoculation
		1 d	4 d	7 d
Normal	4	140.6 ± 7.8	142.1 ± 8.6	141.7 ± 8.4
Infected	5	141.8 ± 9.6	143.5 ± 9.9	142.3 ± 8.7
ORS	5	142.5 ± 8.8	145.8 ± 7.6	144.7 ± 9.2
QWBZP	6	140.6 ± 7.5	141.6 ± 8.6	142.4 ± 8.5

Table 9 Changes of hematocrit after treatment (%, mean ± SD)

Group	n	Days post-inoculation
		1 d	4 d	7 d
Normal	4	42.1 ± 5.6	41.3 ± 4.2	40.5 ± 4.4
Infected	5	43.5 ± 4.8	52.2 ± 5.4a	54.2 ± 5.1a
ORS	5	42.7 ± 5.2	46.7 ± 3.4	46.5 ± 3.7
QWBZP	6	43.9 ± 5.5	45.7 ± 4.7	43.4 ± 4.1

^aP ＜ 0.05 vs normal group.