Differentially expressed genes in hepatocellular carcinoma induced by woodchuck hepatitis B virus in mice

doi:10.3748/wjg.v7.i4.575

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Aug 15, 2001 (publication date) through Nov 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 15, 2001; 7(4): 575-578
Published online Aug 15, 2001. doi: 10.3748/wjg.v7.i4.575

Table 1 Differentially expressed genes in tumor and nontumor liver induced by woodchuck hepatitis B virus

Clone	GeneBank search
Clone	Match	% homology
Tumor^a
T8^b	Human chromosome 1 (UT751,L1637).	54% in 280 bp overlap
T18	Unknown protein, uterine endometrium (x7723)	60% in 151 bp overlap
T19	Ribosomal protein L35A (x03475)	88% in 91 bp overlap
T22	Human T cell receptor beta chain (L166059)	61% in 97 bp overlap
T6	None
T7^b	None
T11^b	None
T24	None
T25	None
Nontumor^a
N7	Human aminopeptidase N (x13276)	93% in 54 bp overlap
N10	Human IFN receptor gene (U10360)	79% in 271 bp overlap
N11	Human glutathione S-transferase (L02321)	75% in 248 bp overlap
N13	Beta-2 glycoprotein 1 from HepG2 (S80305)	79% in 159 bp overlap
N8	None

^aThe clones represent fragments of genes whose expression is activated (T6, T7, T11, T18, T19, T22, T24, T25) or suppressed (N7, N8, N10, N11, N13) in HCC compared to nontumor cells.

^bProbes whose sequences share considerable homology with sequences independently found to be upregulated in HbxAg[+] cells.

Citation: Cao XY, Liu J, Lian ZR, Clayton M, Hu JL, Zhu MH, Fan DM, Feitelson M. Differentially expressed genes in hepatocellular carcinoma induced by woodchuck hepatitis B virus in mice. World J Gastroenterol 2001; 7(4): 575-578
URL: https://www.wjgnet.com/1007-9327/full/v7/i4/575.htm
DOI: https://dx.doi.org/10.3748/wjg.v7.i4.575