Clinicopathological analysis of patients with gastric cancer in 1200 cases

Table 1 Comparison of operation manner with numbers of lymph nodes, time for operation, amount of blood transfusion during operation, hospitalization days and complications (^-x±s_x)

Manners of operation	N (1200)	Numbers lymph nodes	Time for operation (h)	Amount of blood transfusion (mL)	Hospitalization stays (days)	Complication (%)	Positive resection margin (%)
Distal gastrectomy	768	11.7 ± 0.3*	3.3 ± 0.04	426.5 ± 17.1*	16.9 ± 0.7	9.1	3.8
Proximal gastrectomy via abdomen	72	9.6 ± 0.4	4.0 ± 0.1*	629.5 ± 43.3*	18.3 ± 1.5	17*	8.2*
Proximal gastrectomy via thorax	264	8.2 ± 0.2	3.3 ± 0.03	771.5 ± 19.5	15.5 ± 0.6	1.6	8.7*
Total gastrectomy	96	13.8 ± 0.7*	4.6 ± 0.1*	768.2 ± 47.6	19.8 ± 1.7	12.9	9.3*
P		< 0.0001	< 0.0001	< 0.0001	> 0.05	< 0.001	= 0.01

*Compared with other operative approaches.

Table 2 Comparison of depth of infiltration with age, diameter, hemoglobin, and lymphatic metastasis rate (^-x±s_x)

Depth of invasion	N (1200)	Age (yrs)	Diameter (cm)	Hemoglobin(g/L)	Lymphatic metastasis rate (%)
pT1(m)	114	51.6 ± 1.2	2.3 ± 0.4	12.1 ± 0.3	3.2 ± 0.8
pT1(ms)	65	55.7 ± 1.5*	2.5 ± 0.7	11.3 ± 0.4*	4.1 ± 1.3
pT2	91	56.8 ± 1.4*	3.1 ± 0.3	11.2 ± 0.1*	9.8 ± 1.6*
pT3	95	57.1 ± 1.2*	4.2 ± 0.6*	11.4 ± 0.2*	20.4 ± 2.9*
pT4	835	56.9 ± 0.3*	5.6 ± 0.1*	11.2 ± 0.1*	37.1 ± 1.2*
P		< 0.003	< 0.0001	< 0.001	< 0.0001

*Compared with pT1(m).

Table 3 Comparison of differentiation with age, diameter, hemoglobin and lymphatic metastasis rate (^-x±s_x)

Differentiation	N (1200)	Age (yrs)	Diameter (cm)	Hemoglobin (g/L)	Lymphatic metastasis rate (%)
I	37	61.4 ± 1.4	3.5 ± 0.2	10.7 ± 0.4	10.3 ± 3.2*
II	161	57.9 ± 0.8	4.1 ± 0.3	11.1 ± 0.1	26.1 ± 2.5
III	329	58.6 ± 0.7	4.2 ± 0.2	11.2 ± 0.3	22.7 ± 1.4
IV	673	53.2 ± 0.3*	4.9 ± 0.3*	11.8 ± 0.1*	33.6 ± 1.2*
P		< 0.0001	= 0.004	= 0.01	< 0.0001

*Compared with other groups.

Table 4 Comparison of tumor site with age, diameter, hemoglobin and positive lymph node rate (^-x±s_x)

Location of tumor	N (1200)	Age (yrs)	Diameter (cm)	Hemoglobin (g/L)	Lymphatic metastasis rate (%)
Pylorus	27	54.3 ± 2.9	3.9 ± 0.7	12.6 ± 0.7	13.9 ± 3.2
Antrum	379	56.6 ± 0.5*	4.6 ± 0.2	11.5 ± 0.3	26.3 ± 1.4
Incisura	372	54.2 ± 0.4	3.3 ± 0.4	12.5 ± 0.1	22.5 ± 1.3
Corpus	91	55.2 ± 1.2	6.4 ± 0.5*	12.2 ± 0.4	38.3 ± 4.2*
Fundus	331	59.8 ± 0.6*	5.6 ± 0.2*	12.8± 0.2	35.1 ± 1.9*
P		< 0.0001	< 0.0001	> 0.005	< 0.001

*Compared with other locations.

Table 5 Comparison of sex with tumor location, differentiation, depth of invasion and positive lymph node rate (^-x±s_x)

Sex	Location (%)			Differentiation (%)			Depth of invasion (%)			Frequency of metastatic lymph node (%)
	Proximal	Middle	Distal	Well	Middle	Bad	pT1	pT2	pT3	< 30	> 30
Male (836)	31	2	40	18	30	52	14	8	78	64	36
Female (364)	40	3	25	13	21	66	15	7	78	56	44
P	< 0.001			< 0.001			> 0.05			= 0.01

Table 6 Multi-factors analysis of lymphatic metastasis in gastric patients

Related factors	Regression coefficient	Standard error	Standard regression coefficient	P
Constant	-24.3	7.1		0.001
Age	-0.006144	0.079	-0.22	0.438
Sex	-6.489	2.027	-0.092	0.001
Tumor location	2.326	0.780	0.087	0.003
Diameter of tumor	2.368	0.459	0.165	0.0001
Depth of invasion	7.043	0.786	0.285	0.0001
Differentiation	3.687	1.146	0.094	0.001