Expressions of chromogranin A and cathepsin D in human primary hepatocellular carcinoma

Table 1 Relationship between expression of cathepsin D and histologi cal features of HCC

Histologic grade	Expression of cathepsin D
	Positive (%)	Negative (%)
1	1/4 (25.0)	3/4 (75.0)
2	46/53 (86.8)a	7/53 (13.2)
3 + 4	26/28 (92.9)b	2/28 (7.1)

^aP < 0.01 vs Grade 1;

^bP < 0.01 vs Grade 2, 1.

Table 2 Relationship between expression of CgA and histologic grade of HCC

Histologic grade	Expression of CgA
	Positive (%)	Negative (%)
1	3/4 (75.0)	1/4 (25.0)
2	38/53 (71.7)a	17/53 (28.3)
3 + 4	20/28 (71.4)b	8/28 (28.6)

^aP > 0.05 vs Grade 1; P > 0.05 vs Grade 2, 1.

Table 3 Relationship between expression of cathepsin D and CgA in HCC

Expression of CgA	n	Expression of cathepsin D
		Positive	Negative
Positive	61	56	5
Negative	24	15	9
Total	85	71	14