Study on environmental etiology of high incidence areas of liver cancer in China

Table 1 The organic pollution indicators of drinking water and death rate from cancer

The drinking water type	Qidong in Jiangsu					Fusui in Guangxi
	Pond	Channel	River	Shallow well	Deep well	Pond	River	Deep well
Death rate	61.53	58.17	41.99	18.80	0.0	115.05	37.49	0.0
Number of samples	20	18	22	21	16	7	18	25
COD	4.66	3.85	3.55	3.20	1.28	48.27	0.75	0.197
Humic acid	0.43	0.36	0.28	0.18	0.08	0.58	0.18	0.042
NO3-	14.52	18.20	21.46	67.91	1.53	0.74	0.75	0.480
NO2-	0.54	0.48	0.38	0.28	0.04	0.061	0.008	0.0096

The death rate is 1/10⁵ and the unit of NO₃^-, NO₂^- is ppm.

Table 2 The analysis between various drinking water factors and death rate due to liver cancer

Content PPM	Regression a	Coefficient b	Interrelation coefficient r
Humic acid	29.4985	78.6384	0.5981b
NO2-	53.1249	75.9767	0.4232a
COD	43.8098	0.4280	0.4881b
BOD	45.0576	0.6231	0.4872b
DO	191.8340	-19.0087	-0.7285b

^aP < 0.05,

^bP < 0.01, vs control.

Table 3 The content of nitrosamine in pond water and the death rate due to liver cancer in Fusui

Location of samples	Death rate of liver cancer 1/105	Dimethyl nitrosa mine ppb	Diethyl nitrosamine ppb
Sihe	74.96	3.8
Jiuchen	35.42	3.2
Yiliu	31.68	3.6
Mumin	80.80	2.4	2.2
Qutun	112.59	5.6
Zhongyuan	148.49	4.8	2.4
Lailu	95.36	4.2
Jiuta	18.38	0.8	0.4

Table 4 Result of cell mutation test and polluted water samples

Water source type	Cell micronuclei rate %	Cell chromosomal aberration rate %
Pond water 1	63.34	6.42
Pond water 2	59.66	4.76
Shallow well water 1	48.32	3.76
Shallow well water 2	42.66	3.21
Deep well water	3.30	0.75
Blank contrast	2.43	0.17

Table 5 Contrast in water quality before and after the change in water

Test item (ppm)	NO2-	Humic acid	COD	DO	NH4
1	0.0224	0.53	44.24	6.10	0.34
2	0.0106	0.05	0.34	8.21	0.07

Note: 1. pond water, 2. deep well water.

Table 6 Contrast in water quality before and after the change in water

Test item (ppb)	Se	Fe	Mn	Zn	nitrosamine
1	0.56	1110.88	198.33	9.29	4.20
2	0.39	164.60	10.14	50.47	0

Note: 1. pond water, 2. deep well water.

Table 7 Contrast in water quality before and after the change in water

Test item	Plant cell micronuclei rate/%	HHPL
		micronuclei rate/%	chromosome aberration rate/%
1	10.34	59.61	4.76
2	5.96	3.30	0.75

Note: 1. pond water, 2. deep well water.