Immunohistochemical study on p53, H-rasp21, c-erbB-2 protein and PCNA expression in HCC tissues of Han and minority ethnic patients

Table 1 Expression of p53 protein, c-erbB-2, H-rasp21 and PCNA in various liver lesions

Histology	n	p53		c-erbB-2		H-ras		PCNA
		n	%	n	%	n	%	n	%
Tumor (A)	50	23	46.0	35	70.0	34	68.0	41	82.0
Peritumor (B)	50	2	4.0a	11	22.0a	32	64.0c	26	52.0a
Cirrhosis	33	2	6.0	9	27.3	23	70.0	18	54.5
Non-cirrhosis	17	0	0	2	11.8	9	53.0	8	47.0
Normal liver (C)	10	0	0	0	0	3	30.0	0	0

^aP ＜ 0.05, vs A, C;

^cP ＜ 0.05, vs C; χ² test.

Table 2 Expression of p53, c-erbB-2, H-rasp21 and PCNA in HCC of different nationalities

Nationalities	n	p53		c-erbB-2		H-ras		PCNA
		n	%	n	%	n	%	n	%
Han	36	15	39.5	23	60.0	15	39.5	32	84.2
Minority	12	8	66.7a	12	100.0a	9	75.0a	9	75.0
Uygur	8	5	62.5	8	100.0	6	75.0	5	62.5
Kazak	2	1	50.0	2	100.0	2	100.0	2	100.0
Mongolia	2	2	100.0	2	100.0	1	50.0	2	100.0

^aP ＜ 0.05, vs Han, χ² test.

Table 3 The nationality distribution of the combined expression of three oncogenes in HCC

Nationalities	n	p53+c-erbB-2+H-rasp21
		n	%
Han	38	8	21.1
Minority	12	5	41.7