Cultivation of human liver cell lines with microcarriers acting as biological materials of bioartificial liver

Table 1 Changes of specific functions of Cl^-1 under two culture con ditions

Indexes of functions	1st day	3rd day	5th day	7th day	9th day
Albumin synthesis (μg)
Microcarrier culture	21.34	35.87	58.35	71.32	67.98
Common culture	0.43	1.21	1.79	1.65
Urea synthesis (mg)
Microcarrier culture	7.45	11.49	19.62	23.32	20.18
Common culture	0.08	0.34	0.56	0.42
Diazepam transformation (μg)
Microcarrier culture	112.2	271.3	544.1	619.7	573.3
Common culture	3.4	8.9	18.6	13.5

Table 2 Comparison of peak function values of Cl^-1 under two culture conditions

Indexes of functions	Albumin synthesis(μg)	Urea synthesis(mg)	Diazepam transformation(μg)
Microcarrier culture	71.23	23.32	619.7
Common culture	1.79	0.56	18.6
Ratio	39.8:1	41.6:1	33.3:1