Study of differential polymerase chain reaction of C-erbB-2 oncogene amplification in gastric cancer

Table 1 Relationship between clinicopathologic features and incidence of C-erbB-2 amplification

Variable	Case number	C-erbB-2 amplification (%)
		Surgical specimen	Endoscopic specimen
Age (yr)
< 60	16	(31.3)	4 (25.0)
≥ 60	67	19 (28.4)	13 (19.4)
Sex
Male	51	15 (29.4)	10 (19.6)
Female	32	9 (28.1)	7 (21.9)
Gross appearance
Borrmann1	8	3 (37.5)	2 (25.0)
Borrmann 2	37	9 (24.3)	7 (18.9)
Borrmann 3	32	10 (31.2)	7 (21.9)
Borrmann 4	6	2 (33.3)	1 (16.7)
Depth of invasion
Early cancer	28	4 (14.3)a	2 (7.1)a
Advanced cancer	55	20 (36.4)	15 (27.3)
Differentiation
Well-mod	45	17 (37.8)	12 (26.7)
Poor	38	7 (18.4)	5 (13.2)
Lymph node metastasis
Positive	21	11 (52.4)b	7 (33.3)
Negative	62	13 (21.0)	10 (16.1)
Liver metastasis
Positive	13	6 (46.2)	4 (30.8)
Negative	70	18 (25.7)	13 (18.6)

Compared with the other results of same variable group,

^aP < 0.05;

^bP < 0.01. Well-mod: Well to moderately differentiated carcinoma; Poor: Poorly differentiated carcinoma.