Congenital expression of mdr-1 gene in tissues of carcinoma and its relation with pathomorphology and prognosis

Table 1 mdr-1 gene expression in 151 specimens (%)

Site of tumors	n	H	M	L/N	H&M
Esophagus	46	10.9	26.1	63.0	37.0
Gastric cardia	35	17.1	11.9	71.0	29.0
Stomach	16	25.0	12.5	72.5	27.5
Colorectum	16	18.8	12.5	68.7	31.3
Lung	9	22.0	33.0	45.0	55.0
Breast	15	6.6	6.6	86.8	13.2
Thyroid	10	20.0	20.0	60.0	40.0
Uterine cervix	4	0 . 0	0.0	100.0	0.0
Total	151	15.2	18.6	66.2	33.8

H: high expression, M: middle expression, L(N): lower/no expression

Table 2 mdr-1 gene expression in TNM stages of esophageal carcinoma

TNM stage	n	No. of positive cases	Positive rate (%)
IIa	18	6	33
IIb	12	5	40
III	16	6	37

P > 0.05, among the three stages.

Table 3 mdr-1 gene expression in Sun Shao-Qian’s grading system of squamous cell carcinoma of esophagus (n = 17)

Grade	No. of positive cases	Positive	rate (%)
II	6	3	5
II	8	4	0
III	3	3	3

P > 0.05, among the three grades.

Table 4 mdr-1 gene expression in Wu Ying-Kai’s macroscopical typing system of esophageal carcinoma

Types	n	No. of positive cases	Positive rate (%)
Ulcerative	9	3	33
Constrictive	8	3	37
Fungoid	15	5	33
Medullary	14	6	40

P > 0.05, among the four types.