Protection of gastric mucosa from ethanol induced injury by recombinant epidermal growth factor in rats

Table 1 Index of gastric ulcer in all groups (M)

Groups	n	Range	Index
Control (p.o)	9	34-79	58
rhEGF I (30 μg, p.o)	9	6-69	53
rhEGF II (60 μg, p.o)	9	25-59	46b
rhEGF III (120 μg, p.o)	9	0-26	11b
rhEGF IV (60 μg, s.c.)	9	0-29	19b
Cimetidine (p.o)	7	32-52	39a

^aP < 0.05, vs control group;

^bP < 0.01, vs control group.

Table 2 The levels of serum EGF in all groups (ng/L)

Groups	n	Frange	-x±s
Control	9	0.51-0.72	0.63 ± 0.09
rhEGF I	9	6-69	53
rhEGF II	9	25-59	46a
rhEGF III	9	0-26	11
rhEGF IV	9	0-29	19
Cimetidine	7	31-52	39a

^aP < 0.05, vs control group; ^bP < 0.01, vs control group.

Table 3 The values of serum gastrin in all groups (ng/L)

Groups	n	Range	-x±s
Control	6	40-112	75 ± 28
rhEGF I	7	50-160	83 ± 39
rhEGF II	7	46-139	93 ± 43
rhEGF III	7	49-170	80 ± 42
rhEGF IV	6	81-283	149 ± 83a
Cimetidine	6	18-101	49 ± 28

^aP < 0.05, vs control group.