Establishment of a nonradioactive assay for2’-5’ oligoadenylate synthetase and its application in chronic hepatitis C patients receiving interferon-α

Table 1 The digestive results of ATP

The volume of digestion buffer (μL)	0	1	2	3	4	5
Digestive percentage of ATP (%)	0	3.1	18.3	34.1	100	100

Table 2 2-5AS levels in different groups

	Group A	Group B
	Before IFNα stimulation	After IFNα stimulation
n	10	10
x (%)	2.0	19.7
s	0.02	0.09
P	< 0.01

Table 3 2-5AS levels in groups A and B patients (^-x±s)

Group	n	2-5AS level
		prea	24 hb	24 h/pre	1 monthc	1 month/pre
A	9	9.3 ± 4.7%	72.1 ± 15.3%	9.4 ± 4.3	42.3 ± 8.2%	6.2 ± 5.0
B	6	17.5 ± 5.9%	54.1 ± 14.2%	3.4 ± 1.6	37.5 ± 7.0%	2.4 ± 0.8
P		< 0.05	< 0.05	< 0.01	> 0.05	> 0.05

^apre: pre-treatment;

^b24 h: 24 h after first injection;

^c1 month: 1 month after first injection.