Urinary cell-free DNA as a noninvasive liquid biopsy for hepatocellular carcinoma

doi:10.3748/wjg.118587

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 32, Issue 33

This Article

(5)

(0)

(7)

(1)

(115)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Sep 7, 2026; 32(33): 118587
Published online Sep 7, 2026. doi: 10.3748/wjg.118587

Table 1 Detection of cell-free tumor DNA markers by quantitative polymerase chain reaction in matched urine and plasma samples from hepatocellular carcinoma patients (n = 101)

	*TP53*	*CTNNB1*	*TERT*	Total	Cohen’s
Overall concordance % (95%CI), concordant/total	87.8 (78.7-94.0), 72/82	83.3 (69.8-92.5), 40/48	64.9 (53.2-75.5), 50/77	78.3 (72.0-83.7), 162/207	0.565
Positive concordance with at least one positive test (positive agreement) % (95%CI), concordant/total	0.0 (0.0-30.8), 0/10	20.0 (2.5-55.6), 2/10	30.8 (17.0-47.6), 12/39	23.7 (13.6-36.6), 14/59	-0.525

CI: Confidence interval.

Full Size Table

Citation: Kim AK, Lin SY, Liu HN, Jain S, Gade TP, Shieh FS, Hamilton J, Hann HW, Chang TT, Goryunov D, Wang Z, Su YH. Urinary cell-free DNA as a noninvasive liquid biopsy for hepatocellular carcinoma. World J Gastroenterol 2026; 32(33): 118587
URL: https://www.wjgnet.com/1007-9327/full/v32/i33/118587.htm
DOI: https://dx.doi.org/10.3748/wjg.118587

Kim AK, Lin SY, Liu HN, Jain S, Gade TP, Shieh FS, Hamilton J, Hann HW, Chang TT, Goryunov D, Wang Z, Su YH. Urinary cell-free DNA as a noninvasive liquid biopsy for hepatocellular carcinoma. World J Gastroenterol 2026; 32(33): 118587 [DOI: 10.3748/wjg.118587]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.