Rapid progression to liver failure following pancreatoduodenectomy in an adolescent: A case report

Table 1 Dynamics of the patient’s clinical and laboratory parameters

Item	March 27, 2019	June 30, 2019	June 15, 2023	March 6, 2025	Reference
Height (cm)	162	162	174	175	NA
Weight (kg)	50	37	41.8	40	NA
BMI (kg/m2)	19.1	14.1	13.8	13.1	18.5-24.0
ALT (U/L)	11.9	20.5	19.0	12	9-50
ALP (U/L)	261.9	151.1	72.0	96	45-125
TBIL (μmol/L)	13.1	7.1	37.3	85.4	5-21
ALB (g/L)	43.6	37.2	20.2	15.5	40-55
INR	NA	1.24	1.48	2.15	0.85-1.5
PTA (%)	NA	NA	51.4	32.9	70-150
CRP (mg/L)	78.09	3.20	23.98	4.91	0.068-8.2
Cr (μmol/L)	32.4	39.6	29	106	41-109
Ur (mmol/L)	3.8	3.2	0.6	10.8	2.8-7.2
AFP (ng/mL)	NA	1.60	2.9	5.2	< 9.0
WBC (109/L)	6.6	4.3	2.81	1.76	3.5-9.5
Hb (g/L)	94	109	71	22.0	130-175
PLT (109/L)	400	412	111	16	100-300
FPG (mmol/L)	4.8	10.9	3.64	6.31	3.9-6.1
TG (mmol/L)	0.56	0.76	0.59	0.42	< 1.7
TC (mmol/L)	2.25	2.71	1	0.62	< 5.2
HDL (mmol/L)	0.80	0.63	0.37	0.28	0.91-1.55
LDL (mmol/L)	1.23	1.45	0.51	0.32	< 3.4

BMI: Body mass index; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; TBIL: Total bilirubin; ALB: Albumin; INR: International normalized ratio; PTA: Prothrombin activity; CRP: C reactive protein; Cr: Creatinine; AFP: Alpha fetoprotein; WBC: White blood cell; Hb: Hemoglobin; PLT: Platelet; FPG: Fasting plasma glucose; TG: Triglyceride; TC: Total cholesterol; HDL: High-density lipoprotein; LDL: Low density lipoprotein; NA: Not applicable; Ur: Urea.