Successful conversion therapy for advanced hepatocellular carcinoma with biliary tumor thrombus and bilateral lobe involvement: A case report

doi:10.3748/wjg.119220

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastroenterol. Jun 28, 2026; 32(24): 119220
Published online Jun 28, 2026. doi: 10.3748/wjg.119220

Table 1 Baseline and post-treatment characteristics of target lesions

Assessment time	Target lesion location	Maximum lesion size (mm)	AFP level (ng/mL)	CA19-9 level (U/mL)	Liver function grade
Baseline (Jan 2025)	Right hepatic lobe, near hepatic dome	46 × 37	230.00	481.00	Child-Pugh B
After 5 cycles (Jun 2025)	Left hepatic lobe	41 × 43	86.00	7.71	Child-Pugh A

Target lesions were defined as the largest measurable lesions in each hepatic lobe, according to the mRECIST 11 criteria. AFP: Alpha-fetoprotein; CA19-9: Carbohydrate antigen 19-9.

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Citation: Zhang Y, Zhang LY, Meng B, Wang YJ, Yang NM, Li Q, Zhang M. Successful conversion therapy for advanced hepatocellular carcinoma with biliary tumor thrombus and bilateral lobe involvement: A case report. World J Gastroenterol 2026; 32(24): 119220
URL: https://www.wjgnet.com/1007-9327/full/v32/i24/119220.htm
DOI: https://dx.doi.org/10.3748/wjg.119220

Zhang Y, Zhang LY, Meng B, Wang YJ, Yang NM, Li Q, Zhang M. Successful conversion therapy for advanced hepatocellular carcinoma with biliary tumor thrombus and bilateral lobe involvement: A case report. World J Gastroenterol 2026; 32(24): 119220 [DOI: 10.3748/wjg.119220]

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