Multicenter analysis on the correlation between the anatomical characteristics of hepatic veins and hepatic venous wedge pressure

Table 1 Clinical baseline data sheet, n (%)

Variable	Statistics
Age, year, mean ± SD	52.6 ± 13.0
Sex
Male	582 (66.36)
Female	295 (33.63)
Etiology
HBV-related cirrhosis	407 (46.41)
Alcoholic cirrhosis	156 (17.79)
Autoimmune cirrhosis	109 (12.43)
Hepatic veno-occlusive disease	79 (9.01)
HCV-related cirrhosis	46 (5.25)
Cirrhosis of unknown cause	29 (3.31)
Drug-induced cirrhosis	27 (3.08)
Arteriovenous fistula and Wilson's disease, etc.	13 (1.48)
Idiopathic portal hypertension	11 (1.25)
Clinical sign
Gastrointestinal bleeding	453 (51.7)
Ascites	189 (21.6)
Gastrointestinal bleeding + ascites	158 (18.0)
Others (hepatorenal syndrome, hepatic congestion, etc.)	77 (8.8)
Child-Pugh
A	354 (40.4)
B	443 (50.5)
C	80 (9.1)
Group
Hepatic right vein-middle hepatic venous angiography group (group A)	306 (34.9)
Hepatic right vein-accessory hepatic venous angiography group (group B)	219 (25.0)
Hepatic right vein-portal venous angiography group (group C)	177 (20.2)
Hepatic right vein-nonangiography group (group D)	175 (19.9)

HBV: Hepatitis B virus; HCV: Hepatitis C virus.

Table 2 Comparison of the wedged hepatic venous pressure and portal venous pressure among different types of anatomical hepatic venous communication

Variable	PVP	WHVP	U value	P value
Group A	36 (32%-41%)	19 (16%-24%)	3645	< 0.001
Group B	33 (29%-37%)	27 (22%-31%)	11590	< 0.001
Group C	31 (28%-36%)	32 (28%-36%)	16440	0.419
Group D	30 (27%-34%)	36 (32%-40%)	22330	< 0.001

WHVP: Wedged hepatic venous pressure; PVP: Portal venous pressure.

Table 3 Regression analysis of the wedged hepatic venous pressure and portal venous pressure in different hepatic venous anatomic shunt groups

Group	Adjusted R2	Constant	Regression equation	P value
Group A	0.344	24.359	Y = 0.6384X + 24.36	< 0.001
Group B	0.721	11.185	Y = 0.8266X + 11.18	< 0.001
Group C	0.884	1.435	Y = 0.9404X + 1.435	< 0.001
Group D	0.293	15.172	Y = 0.4209X + 15.17	< 0.001

WHVP: Wedged hepatic venous pressure; PVP: Portal venous pressure.