Application of aggregation-induced emission materials in gastrointestinal diseases

doi:10.3748/wjg.v31.i16.105378

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Apr 28, 2025 (publication date) through Nov 2, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2025; 31(16): 105378
Published online Apr 28, 2025. doi: 10.3748/wjg.v31.i16.105378

Table 1 Aggregation-induced emission luminogens show unique benefits in different gastrointestinal tumors

Tumor type	Advantages of AIEgens
OSCC	Avoids other critical areas in the mouth and precisely targets the tumor site for more efficient imaging, diagnosis and treatment
EC	Currently unavailable
GC	Multiplexed assays for plasma markers of gastric cancer, high-contrast imaging, high-sensitivity detection, and synergistic treatment with PDT and PTT
CRC	AIEgens can clearly display tumor boundaries and tiny lesions to assist in early diagnosis, provide dynamic information through real-time imaging

AIEgens: Aggregation-induced emission luminogens; OSCC: Oral squamous cell carcinoma; GC: Gastric carcinoma; CRC: Colorectal cancer; PDT: Photodynamic therapy; PTT: Photothermal therapy.

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Citation: Li YR, Wang G, He WT, Liu T. Application of aggregation-induced emission materials in gastrointestinal diseases. World J Gastroenterol 2025; 31(16): 105378
URL: https://www.wjgnet.com/1007-9327/full/v31/i16/105378.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i16.105378