Altered microbiota of rectal mucosa in rectal cancer patients

Table 1 Clinical characteristics of rectal cancer and healthy subjects, mean ± SD or n (%)

	RC, n = 72	Control, n = 71	P value
Age, year	64.38 ± 11.34	50.10 ± 11.44	< 0.05
Male	52 (72.2)	47 (66.2)	0.435
Female	20 (27.8)	24 (33.8)
BMI, kg/m2	22.41 ± 3.10	22.95 ± 2.24	0.230
TNM stage
I	21 (29.2)
II	15 (20.8)
III	33 (45.8)
IV	3 (4.2)

RC: Rectal cancer; BMI: Body mass index; TNM: Tumor-node-metastasis.

Table 2 Number of microbial communities at different level, mean ± SD

Group	Phylum	Class	Order	Family	Genus	Species
AM	18.9 ± 3.0	37.7 ± 9.5	69.3 ± 21.8	123.1 ± 37.0	212.3 ± 58.5	2316.9 ± 587.4
CM	17.8 ± 2.2	33.0 ± 5.3	57.2 ± 13.2	102.8 ± 21.8	194.3 ± 44.8	2725.6 ± 840.2
NM	13.0 ± 2.5	23.6 ± 4.7	39.4 ± 7.5	74.9 ± 12.3	131.7 ± 21.7	1039.9 ± 243.0

AM: Adjacent noncancerous mucosa; CM: Rectal cancer mucosa; NM: Normal control mucosa.