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©The Author(s) 2024.
World J Gastroenterol. Feb 21, 2024; 30(7): 673-684
Published online Feb 21, 2024. doi: 10.3748/wjg.v30.i7.673
Published online Feb 21, 2024. doi: 10.3748/wjg.v30.i7.673
Table 1 Demographic information, lesion characteristics, and procedural outcomes of early gastric cancer, n (%)
| | GCP (n = 104) |
| Demographic information | |
| Male | 77 (74.0) |
| Age (yr), mean ± SD | 63.4 ± 11.0 |
| History of gastric endoscopic or surgical treatment | 13 (12.5) |
| Symptom | |
| Asymptomatic | 66 (63.5) |
| Epigastric discomfort | 28 (26.9) |
| Regurgitation | 8 (7.7) |
| Melena | 2 (1.9) |
| Lesion characteristics | |
| Growth pattern | |
| Intraluminal growth | 103 (99.0) |
| Extraluminal growth | 1 (1.0) |
| Morphology | |
| Regular | 77 (74.0) |
| Irregular | 27 (26.0) |
| Mucosa | |
| Smooth | 40 (38.5) |
| Ulcerative | 64 (61.5) |
| Max diameter (mm), mean ± SD | 20.9 ± 15.3 |
| Location | |
| Cardia | 40 (38.5) |
| Gastric fundus | 8 (7.7) |
| Gastric body | 35 (33.7) |
| Gastric antrum | 21 (20.2) |
| Endoscopic features | |
| Mucosal lesion type | 62 (59.6) |
| IIa | 29 (46.8) |
| IIa + IIc | 4 (6.5) |
| IIc | 29 (46.8) |
| Polypoid type | 23 (22.1) |
| Submucosal lesion type | 17 (16.3) |
| Thickened mucosa with rough wrinkles type | 2 (1.9) |
| Infiltration depth | |
| Mucosa | 63 (60.6) |
| Submucosa | 40 (38.5) |
| Muscularis propria | 1 (1.0) |
| GCP with EGC | 62 (59.6) |
| Procedural outcomes | |
| Endoscopic methods | |
| Electric cutting | 7 (6.7) |
| EMR | 11 (10.6) |
| ESD | 80 (76.9) |
| ESE | 6 (5.8) |
| En-bloc resection | 95 (91.3) |
| Complete resection | 95 (91.3) |
| Suture method | |
| Unstitched | 62 (59.6) |
| Metal clip | 40 (38.5) |
| Nylon rope | 1 (1.0) |
| Metal clip and nylon rope | 1 (1.0) |
| Surgery time (min), mean ± SD | 73.9 ± 57.5 |
| Complications | 1 (1.0) |
| Hospital stay (d), mean ± SD | 3.4 ± 2.3 |
| Additional surgery | 1 (1.0) |
| Recurrence | 5 (4.8) |
Table 2 Demographic information, lesion characteristics, and procedural outcomes of the early gastric cancer without early gastric cancer s and early gastric cancer with early gastric cancer s groups, n (%)
| | GCP without EGCs (n = 42) | GCP with EGCs (n = 62) | P value |
| Demographic information | |||
| Male | 23 (54.8) | 54 (87.1) | < 0.001 |
| Age (yr), mean ± SD | 58.5 ± 11.9 | 66.7 ± 9.1 | < 0.001 |
| History of gastric endoscopic or surgical treatment | 4 (9.5) | 9 (14.5) | 0.450 |
| Symptom | 0.158 | ||
| Asymptomatic | 23 (54.8) | 43 (69.4) | |
| Epigastric discomfort | 15 (35.7) | 13 (21.0) | |
| Regurgitation | 4 (9.5) | 4 (6.5) | |
| Melena | 0 (0) | 2 (3.2) | |
| Lesion characteristics | |||
| Growth pattern | 1.000 | ||
| Intraluminal growth | 42 (100) | 61 (98.4) | |
| Extraluminal growth | 0 (0) | 1 (1.6) | |
| Morphology | 0.007 | ||
| Regular | 37 (88.1) | 40 (64.5) | |
| Irregular | 5 (11.9) | 22 (35.5) | |
| Mucosa | < 0.001 | ||
| Smooth | 27 (64.3) | 13 (21.0) | |
| Ulcerative | 15 (35.7) | 49 (79.0) | |
| Max diameter (mm), mean ± SD | 18.0 ± 14.4 | 22.9 ± 15.7 | 0.110 |
| Location | 0.003 | ||
| Cardia | 9 (21.4) | 31 (50.0) | |
| Gastric fundus | 7 (16.7) | 1 (1.6) | |
| Gastric body | 16 (38.1) | 19 (30.6) | |
| Gastric antrum | 10 (23.8) | 11 (17.7) | |
| Endoscopic features | < 0.001 | ||
| Mucosal lesion type | 8 (19.0) | 54 (87.1) | |
| IIa | 6 (75.0) | 23 (42.6) | |
| IIa + IIc | 0 (0) | 4 (7.4) | |
| IIc | 2 (25.0) | 27 (50.0) | |
| Polypoid type | 19 (45.2) | 4 (6.5) | |
| Submucosal lesion type | 13 (31.0) | 4 (6.5) | |
| Thickened mucosa with rough wrinkles type | 2 (4.8) | 0 (0) | |
| Infiltration depth | 0.363 | ||
| Mucosa | 24 (57.1) | 39 (62.9) | |
| Submucosa | 17 (40.5) | 23 (37.1) | |
| Muscularis propria | 1 (2.4) | 0 (0) | |
| Procedural outcomes | |||
| Endoscopic methods | < 0.001 | ||
| Electric cutting | 7 (16.7) | 0 (0) | |
| EMR | 11 (26.2) | 0 (0) | |
| ESD | 18 (42.9) | 62 (100) | |
| ESE | 6 (14.3) | 0 (0) | |
| En-bloc resection | 38 (90.5) | 57 (91.9) | 1.000 |
| Complete resection | 38 (90.5) | 57 (91.9) | 1.000 |
| Suture method | 0.011 | ||
| Unstitched | 18 (42.9) | 44 (71) | |
| Metal clip | 23 (54.8) | 17 (27.4) | |
| Nylon rope | 1 (2.4) | 0 (0) | |
| Metal clip and nylon rope | 0 (0) | 1 (1.6) | |
| Surgery time (min), mean ± SD | 38.5 ± 38.6 | 96.6 ± 56.3 | < 0.001 |
| Complications | 1 (2.4) | 0 (0) | 0.404 |
| Hospital stay (d), mean ± SD | 2.6 ± 1.8 | 3.9 ± 2.5 | 0.006 |
| Additional surgery | 0 (0) | 1 (1.6) | 1.000 |
| Recurrence | 2 (4.8) | 3 (4.8) | 1.000 |
Table 3 Multivariate logistic regression analysis for gastric cystica profunda with early gastric cancers
| Factors | Multivariate analysis | ||
| OR [95%CI] | β coefficient | P value | |
| Location | |||
| Cardia | 1 | ||
| Non-cardia | 0.881 [0.226-3.424] | -0.126 | 0.853 |
| Sex | |||
| Male | 3.323 [0.771-14.764] | 1.201 | 0.104 |
| Female | 1 | ||
| Morphology | |||
| Regular | 1 | ||
| Irregular | 15.278 [2.965-111.712] | 2.726 | 0.003 |
| Endoscopic features | |||
| Mucosal lesion type | 1 | ||
| Non-mucosal lesion type | 0.029 [0.006-0.108] | -3.531 | < 0.001 |
| Age | 1.026 [0.968-1.090] | 0.025 | 0.392 |
- Citation: Geng ZH, Zhu Y, Fu PY, Qu YF, Chen WF, Yang X, Zhou PH, Li QL. Endoscopic features and treatments of gastric cystica profunda. World J Gastroenterol 2024; 30(7): 673-684
- URL: https://www.wjgnet.com/1007-9327/full/v30/i7/673.htm
- DOI: https://dx.doi.org/10.3748/wjg.v30.i7.673