Hepatic arterial infusion chemotherapy and embolization in the treatment of primary hepatic carcinoma

Table 1 Findings on hepatic arteriography in 188 cases of primary hepatic carcinoma

Findings	Cases	%
Tumor stain	186	98.9
Tumor vessels	180	95.7
Displacement and distortion of arteries	128	68.1
Pool or lake-like collections	114	60.6
Vascular encasement	106	56.4
Tumor thrombus within portal vein	96	51.1
Extrahepatic metastases	32	17.0
Arteriovenous fistula	24	12.8

Table 2 Changes intumor size in the hepatic arterial infusion chemotherapy and hepatic arterial embolization groups

Group	n	Tumor shrinking rate			No change	Enlargement
		≥ 50%	25%-50%	< 25%
HAI	80	2	8	59	7	4
HAE	102	78	12	3	5	4

Chi-square test value = 110.1, P < 0.01. HAI: Hepatic arterial infusion chemotherapy; HAE: Hepatic arterial embolization.

Table 3 Effects of different methods of treatment

Methods of treatment	n	Survival rates (%)				Mean survival time (mo)
		6 mo	12 mo	24 mo	36 mo
HAI	82	61.0	25.4	4.5	0	7.7
HAE	106	86.8a	61.7	37.8	26.1	15.7
HAE-Lp-GS	50	80.0	48.9	31.1	0	11.1
HAE-Lp-BS	56	92.9b	81.9	44.9c	33.6	19.8

Note:

^bP > 0.05, ^a,cP < 0.05, others P < 0.01. HAI: Hepatic arterial infusion chemotherapy; HAE: Hepatic arterial embolization.

Table 4 Factors influencing survival rate

Factors	n	Survival rate (%)
		6 mo	12 mo	24 mo	36 mo
Clinical stages
II	112	88	60	33	19
III	68	53	17	0
Pathological types
Nodulous	28	83	53	24	19
Massive	128	77	48	27	15
Diffusive	32	56	23	0
Mass diameter (cm)
< 5	10	100	100	62	54
5-10	78	85	61	32	18
≥ 10	100	66	29	11	0
Treatment time
1	58	45	0
2	48	79	48	23	0
> 2	82	95	78	39	26
Tumor thrombi
(+)	96	65	28	3	0
(-)	92	87	65	39	23
Liver cirrhosis
None or mild	109	87	68	39	24
Moderate or severe	79	39	18	4	0

Note: Between the nodulous and the massive type, P > 0.05. Others, P < 0.05 or 0.01.