Global trend and future landscape of intestinal microcirculation research from 2000 to 2021: A scientometric study

Table 1 The top 10 countries and institutions contributed to publications on intestinal microcirculation

Rank	Country	Count	Institution	Count
1	United States	420	Dalhousie Univ	41
2	Germany	231	Univ Szeged	35
3	China	164	Univ Amsterdam	33
4	Japan	113	Louisiana State Univ	31
5	England	77	Med Coll Wisconsin	29
6	Canada	69	Univ Louisville	29
7	Italy	67	Univ Munster	23
8	Netherlands	63	Univ Sao Paulo	23
9	France	51	China Agr Univ	20
10	Sweden	47	Lund Univ	20

Table 2 The top 10 journals and cited journals of intestinal microcirculation research

Rank	Journal	Count	Cited-journal	Count
1	Shock	53	Nature Reviews Microbiology	2930
2	Journal of Surgical Research	37	Clinical Microbiology Reviews	1533
3	World Journal of Gastroenterology	36	Journal of Pathology	1520
4	American Journal of Physiology-Gastrointestinal and Liver Physiology	34	Critical Care Medicine	1499
5	Critical Care Medicine	34	Gastroenterology	1372
6	Clinical Hemorheology and Microcirculation	27	American Journal of Physiology-Gastrointestinal and Liver Physiology	1175
7	Microcirculation	20	World Journal of Gastroenterology	1126
8	Microvascular Research	95	Science	968
9	Plos One	73	Shock	965
10	American Journal of Physiology-Heart and Circulatory Physiology	70	Journal of Immunology	937

Table 3 Top 10 highly cited publications in intestinal microcirculation

Rank	Title	Citations	Journal	First author	Published year
1	Enhanced Leukocyte Binding by Intestinal Microvascular Endothelial Cells in Inflammatory Bowel Disease	65	Gastroenterology	David G. Binion	1997
2	Intestinal mucosal lesion in low-flow states	62	Archives of Surgery	Chu-Jeng Chiu	1970
3	The microcirculation is the motor of sepsis	49	Critical care	Can Ince	2005
4	Microvascular Blood Flow Is Altered in Patients with Sepsis	46	American Journal of Respiratory and Critical Care Medicine	Daniel De Backer	2002
5	How to evaluate the microcirculation: report of a round table conference	45	Critical care	Daniel De Backer	2007
6	Preparation of rat intestinal muscle and mucosa for quantitative microcirculatory studies	43	Microcirculation research	H.Glenn Bohlen	1976
7	Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock	42	Critical care medicine	Yasser Sakr	2004
8	Microcirculatory oxygenation and shunting in sepsis and shock	34	Critical care medicine	Can Ince	1999
9	Angiogenesis as a Novel Component of Inflammatory Bowel Disease Pathogenesis	32	Gastroenterology	Silvio Danese	2006
10	Ischemia–Reperfusion Injury of the Intestine and Protective Strategies Against Injury	32	Digestive Diseases and Sciences	Ismail Hameed Mallick	2004

Table 4 Top 10 keywords in terms of frequency

Rank	Frequency	Centrality	Keywords
1	136	0.05	Expression
2	136	0.04	Nitric oxide
3	134	0.06	Blood flow
4	109	0.05	Rat
5	106	0.03	Injury
6	100	0.04	Microvascular endothelial cell
7	100	0.08	Inflammatory bowel disease
8	92	0.06	Microcirculation
9	85	0.08	Sepsis
10	85	0.05	Septic shock