Review of ferroptosis in colorectal cancer: Friends or foes?

doi:10.3748/wjg.v29.i3.469

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Jan 21, 2023 (publication date) through Oct 30, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2023; 29(3): 469-486
Published online Jan 21, 2023. doi: 10.3748/wjg.v29.i3.469

Table 1 Prognostic model of ferroptosis-related genes in colorectal cancer patients

Model	Related genes	Ref.
10-Gene prognostic model	TFAP2C, SLC39A8, NOS2, HAMP, GDF15, FDFT1, CDKN2A, ALOX12, AKR1C1, ATP6V1G2	[11]
Prediction model based on CDRG¹ regression analysis	ACAA2, SRI, UGT2A3, KPNA2, MRPL37	[12]
Prognostic model based on EMT¹ and FRGs¹	MMP7, YAP1, PCOLCE, HOXC11	[13]
Prognostic model of 4-FRL¹ signatures	AP003555.1, AC104819.3, LINC02381, AC005841.1	[155]

¹CDRG: Colorectal cancer differentiation-related gene.

EMT: Epithelial-mesenchymal transition; FRG: Ferroptosis-related gene; FRL: Ferroptosis-related lncRNA.

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Citation: Wu Z, Fang ZX, Hou YY, Wu BX, Deng Y, Wu HT, Liu J. Review of ferroptosis in colorectal cancer: Friends or foes? World J Gastroenterol 2023; 29(3): 469-486
URL: https://www.wjgnet.com/1007-9327/full/v29/i3/469.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i3.469