Computed tomography perfusion in liver and spleen for hepatitis B virus-related portal hypertension: A correlation study with hepatic venous pressure gradient

Table 1 Characteristics of the patients

Characteristic	Value
Sex as female/male, n	4/24
Age, yr, mean ± SD	53.7 ± 10.4
Height, cm, mean ± SD	169.4 ± 5.8
Weight, kg, mean ± SD	62.9 ± 11.6
Previous episodes of variceal bleeding, mean ± SD	3 ± 2
Treatment history, n (%)
β blockade only	3 (10.7)
Sclera therapy only	4 (14.3)
β blockade and sclerotherapy	21 (75.0)
Child-Pugh stage, n (%)
A	11 (39.3)
B	16 (57.1)
C	1 (3.6)
Ascites, n (%)
None	17 (60.7)
Mild	2 (7.1)
Severe	9 (32.1)
HVPG, mmHg, n (%)
< 12	10 (35.7)
≥ 12	18 (64.3)

HVPG: Hepatic venous pressure gradient; SD: Standard deviation.

Table 2 Comparison of the moderate and severe portal hypertension groups

Index	Moderate PH	Severe PH	P value
Sex as female/male	2/8	2/16	0.520
Age, yr	54.2 ± 10.9	53.4 ± 10.5	0.848
Height, cm	168.0 ± 6.0	170.1 ± 5.6	0.362
Weight, kg	64.8 ± 12.3	61.8 ± 11.4	0.528
Child-Pugh score	7.1 ± 1.9	7.8 ± 1.8	0.023
HVPG	9.6 ± 1.3	18.9 ± 4.4	0.000
Perfusion CT
LBF	114.6 ± 36.0	87.9 ± 24.8	0.029
LBV	19.7 ± 3.0	15.5 ± 2.2	0.000
HAF as × 10-2	8.2 ± 2.3	8.7 ± 4.7	0.731
SBF	96.0 ± 30.0	108.7 ± 31.4	0.308
SBV	13.9 ± 2.9	11.9 ± 2.5	0.084

Data are presented as n or mean ± SD. CT: Computed tomography; HAF: Hepatic arterial fraction; HVPG: Hepatic venous pressure gradient; LBF: Liver blood flow; LBV: Liver blood volume; PH: Portal hypertension; SBF: Splenic blood flow; SBV: Splenic blood volume.